Honestly i don't know of anything else besides zofran and phenergan, and phenergan is alot worse about making you sleepy. Have you asked your doctor about maybe cutting your pills in half? I dont know how well it will work with the hypermesis, as nothing worked for mine. But it may help you. Also you may be able to do b6 with half a zofran and it have the same effect, just not as tiring.
Tried the unisom and b6 and it didnt work. I would just throw it up
I had hyperemesis as well, my doc put me on 50mg vitamin B6 and one half of a 25mg tablet of unisom before bedtime every night. It worked wonders for me! I was on bedrest from weeks 11-17. I still had some nausea throughout the day but it was a lot more bearable since I couldn't take the zofran daily.
Mine is the off brand of zofran too. I just have to keep it in my system which is why its making me so tired I think
I took Ondansetron. They're generic for Zofran.. They were 8mg dissolvable tablets & they worked great ! I never had any morning sickness but on the days I didn't feel good, these really helped.
I don't know if its available where you are but ask your doctor about Diclectin. I took that in my first two trimesters because I couldn't keep anything down. I didn't have hyperemesis, just really bad morning sickness.