This seems like an odd question, but since I am affected by this, here goes. My RLS is in high gear about 4 days before and 4 days after the full moon. I had been on Requip for about 2 years and although it was helpful, those 8 days the medication did not seem to help. My health care company decided that Requip is no longer a formulary drug,so I have switched to benztropine. Unfortunately, I had to switch during the last full moon and really did not get but a couple hours of sleep for 3 days. The beztropine seems to help, although I think I'm having some side effects from it. We are approaching the full moon again, so I'll see what this medication can/cannot do. Does anyone else have this problem?