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Antibodies high

I just got my test results back.  Could someone please explain what this means for me?

T3-Free is 1.554 which appears to be in the normal range.
Thyroglobulin Antibody is 129.4  which is high.
Throid Peroxidase (TPO) is 1813.7 which is extremely high!
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Avatar universal
        T4,FREE 1.1                                0.7 - 1.8 ng/dL

        TSH 3.59                                        0.34 - 2.50 UIU/mL

         THYROPEROXIDASE ABY 84.4       < 34.0 -   IU/mL

these are my results...my dr says i dont need to take any meds..but  thati need  to check yearly..

my concern is tht i will soon be planning to have kids,and i was thinking tht its better to be hyper by takin meds,than to be hypo and affect the fetus.

could anyone who's been thr same ,or a dr suggest me something..

thanks in advance.
Helpful - 0
Avatar universal
HI,

My wife has hypothyroid and high level of antibodies; doctors have said that this could be the reason for infertility. She has been taking medicine for antibodies, but nothing seems like working. Any advice would be appreciated.

Thanks,
RG
Helpful - 0
665125 tn?1273023924
This has been my Hashimoto's Thyroiditis journey.....

I was diagnosed 4 years ago with "Hashimoto's Thyrioditis", when diagnosed my thyroid anti-body count was in the 1000's, the normal range was <less than 35. My TSH and
F-T4 were both in the normal range.

My GP sent me to see a ENDO immediately...

The ENDO ordered an Ulra Sound, a singular 1.0cm Thyroid Nodule was discovered. Next, the ENDO ordered a FNAB to check the nodule for cancer cells, pathology reported that the nodule was benign. The ENDO explained to me that small nodules, even a cluster of nodules is typical find with Hashimoto's, however, a singular large nodule is suspicious of cancer. Because of the suspicious nature I would have to have a Ultra Sound and FNAB every 6 month.

At this time the ENDO put me on 25mcg of Synthroid because although my TSH and
F-T4 levels were in the normal range. Within a 4 year period of time my dose of Synthroid was increase from 25mcg, to 50mcg, then 75mcg, then 100mcg, then 125mcg,  this is called "TSH Suppression Therapy".  The ENDO was attempting to shrink the nodule by the use of this therapy. During which, the nodules did not shrink in size, however, it did remain the same size for 3 of the 4 years. And although my Synthroid dose was continuely increased my TSH and F-T4 always remained in the normal range.

I was told that my Thyroid Anti-Bodies, did not need to be continuely checked because they can change daily. The Thyroid Hormones do not have anything to do with the Thyroid Anti-bodies.  If one has Hashimoto's you are going to have the Thyroid Anti-bodies. These Thyroid Anti-bodies, they as we know have the wrong message and the message is to distroy the Thyroid for they think it is an intruder, an enemy!

My ENDO had been telling me all along that a benign report of a FNAB is non- conclusive. That all regions of the nodule can not be checked and in a large nodule cancer cells can be hidden. So my ENDO constantly encouraged surgery, for this reason and also for the reason that Hashimoto's never just goes away and eventually my Thyroid would be dormant. Why continue to chance cancer, why continue having to have FNAB etc.

I was also suffering from what is called "Thyroid Storms", this is when ones Thryoid is nearly dormant, yet sputters now and then. When the Thyroid sputters it releases T4, so while taking a regulated dose of Thyroid Hormone which is (T4), and then the Thyroid sputters and released more T4 you are now on a rollercoaster!  

The 4th year...  My Thyroid Nodule suddenly got larger despite the "TSH Suppression Therapy", I now had a 2.0cm nodule. After meeting someone like myself that also had a benign FNAB and ended up with hidden cancer cells. I chose to just get it over with!

I am now 5 weeks post-opp for a "Complete Thyroidectomy", pathology found NO CANCER CELLS, thank GOD !  

Just recently I read information that taking a supplement of Selenium can lower your Thyroid Anti-bodies. I do not know if this is true, but it is worth checking out....  If true maybe one can slow down the distruction and eventual death of their Thyroid.

Good Luck!   Sonflower
Helpful - 0
213044 tn?1236527460
That last sentence is probably incorrect.
All cells need T3, so antibodies would need T3 as well.

It doen't change the rest of my thoughts, though.

As far as suppresed TSH and Hashimoto's- the only time doctors aim for a suppressed TSH is for a patient who has had thyroid cancer.

Hashimoto's is THE MOST COMMON form of hypothyroidism. Most people with hypothyroidism have Hashimoto's. The target range of TSH is 1.0 or 1.5, with adjustments made from there based on lingering symptoms.
Helpful - 0
213044 tn?1236527460
That is true, but think about it.

If your levels are truly good, starting meds would drive you hyper.

Personally I think it is a matter of doctors not knowing what proper levels are. That would explain why starting medication "early" would be of benefit. It would also explain why some doctors think antibodies can cause symptoms.

Just my opinion. You can find material supporting either line of reasoning. I feel strongly that if you take levothyroxine, you either need it or it will drive you hyper. Antibodies are not going to absorb hormones you do not need and then behave even though their concentration has not changed. Antibodies ar not going to absorb the T4 at all, period.
Helpful - 0
670955 tn?1226597900
I took self off thyroid meds one time because I was feeling hyper. The next time I did TSH I was 11. something or another, normal range .3 to 3, so going off levothyroxine is not an option in this lifetime. Current TSH is .7, but I do not feel well at that range either.

I have read that you can have symptoms with high anitibodies while TSH is in normal range. There seems to be some discussion in medical circles about whether treating with thyroid meds would prevent thyroid dysfunction in future, whether symptoms are present or not, because eventually, the thyroid will dysfunction with Hashimoto's. It's just a matter of time.
Helpful - 0
213044 tn?1236527460
Rainydeb,

You do not need to have your TSH suppressed if you have Hashimoto's. The target is a normal TSH, something between 0.8 and 1.8.

Antibodies do not cause symptoms that can be treated with thyroid medication. Levothyroxine is simply a hormone. It will give you more hormone, but it does not affect antibody count or activity in any way.

If your hormones levels are good taking levothyroxine will make you feel worse, not better.

virgo2121,

your tests are a little confusing. It looks like they ran two TGab tests on the first round of tests, but they didn't.

TGab is antithyroglobulin. You list two tests with the same limits, but different results. I think the TGab must be a TG test, and you typed it out wrong, maybe?

Your TPOab changing is not unusual. It is on the rise now. It can fluxuate up and down. The lower it is, the better off you are. It may hover where it is, or it may go up or down.

The only disturbing thing is your last Free T4, which is getting rather high. I assume you had been on the medication for a month between tests. You should get your TSH and your Free T4 checked again in another month or so, about every six weeks until you know the med doseage is correct.

As far as ranges, different labs use different ranges. That's why it is nice to list the lab ranges when you list test results.
Helpful - 0
Avatar universal
I have been recently diagnosed with hashimotos disease.  My test results on 20/9/08 were:

TSH = 1.93 mU/L       (normal range 0.40 - 4.00)
Free T4 = 13 pmol/L   (normal range 9.0 - 19.00)
TPO Ab 239  IU/mL    (normal range <5.6)
TG Ab 17.0 IU/mL       (normal range 1000 IU/mL (normal range <61)
Antithyroglobulin     was 162 IU/mL (normal range <61)


I had my tests re done on 29/10/08 with a different laboratory and was devastated when results where mega different. However, the normal range also differs on some of the tests here which makes it hard to interpret:

TSH = 1.84 mU/L (normal range 0.40 - 4.00)
Free T4 = 23 pmol/L   (normal range 10.0 - 25.00)
Antithyroid Peroxidase (TPO) was 402  U/mL (normal range 0 - 35)
They did not do TG Ab on this one




What confused me is that the normal range for different labs differed remarkably.

My endo has put me on 50 Oroxine 50mcg T which I think is another name for Thyroxine sodium. He was not going to treat me initially but I pushed for some treatment as I am doing IVF and want to make sure I am in the best health and want to save my thyroid!

Am I on the right treatment to save my thyroid or should I be on something else?

Any replies I would be grateful for.



Helpful - 0
670955 tn?1226597900
I have Hashimoto's, and I know it has not been treated correctly in the past, but I am a little confused also.

With Hashimoto's, we want TSH suppressed? My idiot endo said that's why she didn't want me adding T3 because it would suppress my TSH. She will only do TSH testing, even though now I am taking Cytomel with Levothyroxine.

Also, I read....somewhere...that if antibodies are high, you can have hypo symptoms while TSH shows normal. If that's the case, why in the world will some doctors only do TSH testing for those of us with Hashimoto's, while implying our symptoms are all in our heads???
Helpful - 0
Avatar universal
Thanks so much for the information!  

I'm so new to this that I just wasn't sure what everything means.

This forum is AWESOME!!!
Helpful - 0
499534 tn?1328704178
Ahaa....makes more sense now....lol  With hashis you want your tsh suppressed as far as you can handle it....with synthetics .50-1.0. Now, knowing you are on armour the levels go into a diff ballgame. Your tsh will look hyper and your t3 will be top normal range and t4 mid normal when you reach optimum level. It sounds like you have a good dr....wow! Glad you are feeling good. The sooner you catch hashi's and treat it the better. For those of us who weren't treated right away and stayed sick for a while it is much harder to recuperate and heal. If you would like to learn more about armour, just go to the top rt area of this page and click on health pages. Then look for the armour information page. At the bottom of page is also the link to take you to the actual prescribing information page for your dr. You can print that. Good luck!!
Helpful - 0
213044 tn?1236527460
All your thyroid test numbers are in the normal range.
Not just "in the normal range", but good.

I think putting you on medication was a little premature.
Time will tell.

Your antibody numbers are not so normal. As Laura said, they indicate Hashimoto's, an autoimmune thyroid condition. The high TPOab may make it a bit harder to control the disease than if that result was lowered by half.
Helpful - 0
Avatar universal
I'm sorry...I got the numbers wrong.

My T3-Free is 3.46 and my TSH-3rd Generation is 1.554.  Whatever that means...

My Doc put me on 30 mg of Armour before we even got the blood work done.  They just mailed them to me...so I haven't talked to him since the results came in.  The nurse said that he would most likely increase the dose.  I won't find out until my appointment on the 18th.  Although I have to say that I am already feeling better.  More energy!  Which is amazing considering I have only been on it for 8 days.
Helpful - 0
499534 tn?1328704178
Your antibody tests show positive for hashimotos autoimmune disease.  Your Free
T3 is low even though it shows in low normal range. Where is your TSH and Free T4 results? Cannot get a complete picture without those. I would "guess" that you are hypothyroid from your t3 range.....are you on thyroid meds? Need more info please. :) :)
Helpful - 0
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