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Can Dessicated Thyroid or T3 exaust adrenals for some?

Hi, sorry for my english , i am italian .
i had Graves 11 years ago and underwent RAI. Since then i have been on T4 therapy . Since July 2014 i switched to Natur Throyd because i was not converting T4 in T3 very well, in fact my FT4 labs were 59% of the normal range but the FT3 were at the buttom of the range. NDT improved a lot with cognitive functions , my energy, my period became regular again (I am 50) and helped me with other syntoms like being always cold. bUT NDT only gave me heart race and anxiety so I cut some NTD and added some levothyroxine. I had optimal result and good labs on this mix but still i was too reactive, agressive and easy to be stressed. Then i shifted to syntetic T4+T3 but still i could not find the right dose i ended up after 11 months of NTD or T4+T3 very very stressed and after a hard work month i was KO. This made me wonder if maybe I cannot stand T3 even in small doses (in the last month i was taking 10 or even 5 mcg T3).
I had the proof of this when i quit T3. Now i am on T4 only but hypo syntoms came back (anyway better a little bit hypo then stressed and angry in my opinion) Now the question is: Does this often or sometime happens to adrenal weak people? (or if you prefer easily stressed people like me) . I read a lot about adrenal and thyroid issues lately: on the STTM site is written that even adrenals need T3 so the way to restore exausted adrenal is throug NTD but I don'l trust much that site. I have the feeling that NTD or T3 are not good for adrenals . Does anybody has some knowledge  or experience,  with this issue?
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Avatar universal
Hi I too am on NT just wondering if you are splitting your dose. I take only 3- 1/4 grain pills in the morning and 4- 1/4 grains in the afternoon. Sometimes in the morning when I drink tea I notice I get a bit hyper but I think that's from the tea, most times I'm really good. I'm now taking 1- 1/4 grain before bed because my t4 is real low, and it didn't effect my sleep. At first I was to take 4 in the morning which was at that time too much, so you kind of have to see what feels right. I had a horrible time with levothyroxine t4 meds. very happy with NT also if you do go back on NT make sure you don't take it before you have labs drawn otherwise you'll get a very high FT3 good health deb
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Avatar universal
Thank you for your answer!
I am already taking ViT D And. B12 . Ferritine is relatively low but i cannot supplement because of Hepatite C. I am surprised that not everybody taking NDT or T3 experience nervousness and agressivity because this is what I do. I will check my adrenal function with blood lab but i am rather sure that they are weak (when i was 25 i sometime came back from work vomiting and feeling strong nausea, the doc would shot me some adrenal extract and i was feeling well immediately...since that period that disrupted my balance , stress never left me... before the Graves i staid  2 years in a buddist monastery and i have never been so healthy like in those 2 years...when i got back to the stressfull job , after 2 years i got Graves....what i mean is that stress is a big issue for my body  and when i take T3 i become so easily stressed....sorry for repeating the same word so many times but stress and adrenal are so connected...thank you for the information about ferritin....once i took iron supplement for some days out of ignorance about the liver risk and i was feeling so well...i love iron ...but when i told it to the doc he got angry and he stopped me immediately :-(
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Avatar universal
Before concluding that there is an adrenal issue, I wondered if you have been tested for Vitamin D, B12 and ferritin.  Hypo patients are frequently too low in the ranges for those, which can cause symptoms that mimic hypothyroidism.  Also, Vitamin D and ferritin are important for metabolizing thyroid hormone.  

I don't know why there would be a reaction to T3 itself, since the body converts T4 to T3 on a continuous basis.  I have read that hypo patients that are too low in ferritin sometimes have unwanted reactions to increases in T3 med.  
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