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How should I handle this? Too much T3 on current synthroid dose

I've pushed myself to become hyper as I've been working on raising my T3 and reducing my synthroid (I will try NDT down the line but I've had a lot of health issues lately with my type one diabetes and PCOS and am not ready to make that big of a switch quite yet). I got overzealous with adding too much t3 too quickly. Over the course of the last month I raised my t3 from 20 mcg to 30 mcg (synthroid was dropped at same time from 150 to 137) and was feeling amazing and then suddenly last week I was dealing with lots of hyper symptoms. I've already slightly reduced my t3 the past few days from 30mcg to 25mcg when I realized what was happening and my endo now has me on synthroid 125 as of yesterday.

I know I'll feel crappy for a few days as things adjust, and I dont want to reduce my T3 too much during this transition because my body seems to love it and I'm freezing and chronically constipated without it, but would it help to reduce my t3 dose even more for a week or so? OR should I skip my synthroid for a few days and just keep my T3 where it is right now (25mcg)? What would reduce the hyper symptoms quicker? I take total responsibility for putting myself in this predicament, but I was sick for over 11 months last year and was so grateful to finally feel better for once! I've learned my lesson now.

Last labs were done on 11/29 and were the basis for agreeing to lower synthroid from 150 to 137 and I was given the green light to increase my cytomel until I felt optimal: T3 Free: 2.8 pg/ml (1.7 - 3.7 pg/ml) T4 Free: 1.0 ng/dl (0.7 - 1.5ng/dl)
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Avatar universal
Propranolol is prescribed by doctors for both anxiety, high blood pressure, fast heart rate and other hyper symptoms. Its a safe choice unlike other BP lowering medicines. You can ask your doctor to prescribe you one at low dose until the medication effect subside.
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649848 tn?1534633700
COMMUNITY LEADER
When you make a change in your dose of Synthroid (or other T4 medication), it takes 4-6 weeks for the change to take effect.  When you make a change in T3 medication, it takes effect immediately, because the half life of T3 is only about a day, whereas the half life of T4 is 5-7 days. That means it takes your dosage 5-7 days to reduce by half...

30 mcg is a very high dose of T3 and I'm surprised your endo even considered letting you go that high with a Free T3 that was already at 55% of its range. Your body might like T3, but not that much... :-)

It bothers me that your endo dropped your Synthroid to 137 mcg when your FT4 was only 1.0 back in November... T3 med isn't usually added to a regimen unless FT4 is mid range or higher and FT3 is staying very low, which indicates lack of conversion.   Your FT4 was only at 38% of its range, when it should be at least mid range and your FT3 was already, at 55%, which indicates your conversion wasn't that bad and you probably don't need that much T3.  There has to be a balance between FT4 and FT3 in order for you to feel well; you didn't have that and you probably still don't, because all that T3 would have increased your FT3, but dropping your Synthroid dose may have decreased your FT4 level even further than it was in November.

If I were you, I'd go get a new set of labs, before I changed anything else, so I could see exactly "what" I needed to change... In the meantime, I might drop the T3 med by another 5 mcg, but I wouldn't make any huge changes, until I got lab results back.  

One question is whether or not you split your T3 dosage into more than one dose/day or if you take it all at once.  Most of us find that splitting it into 2 doses, with 1/2 taken first thing in the morning, with our T4 dose and the other 1/2 taken about noon or early afternoon spreads out the T3 and keeps FT3 levels stable throughout the day and prevents us from getting the whole slug of T3 at one time...
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