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HASHITOXICOSIS or Graves's disease
I had muscle pain and cramps, constipation for last 3-4 months. I also have excessive hairloss. My pulse is 72/min regular. I get heat intolerance only when driving for long time in heating on car in winter. I also have depressive symptoms including loss of libido. Also now first time in my life I have delayed menses. I do not have any palpable goitre or neck swelling, My CBC is normal. ESR is 21 instead of upper limit of 20. I do not have any eye signs as per my doctor and do not have any palpitation. My tests for arthritis panel was negative.
My thyroid function were normal during annual in april 2008. On this March 2009, I had T4 level -13.7, T3- 41 and TSH very low. FTI was 5.6 and high. My TPO was more than 1000 and TSH immunoglubin was negative. I am still awaiting report on my RAIU. My doctor is considering Hashitoxicosis vs. Graves disease. I am 43 and had permanent sterilization 5 years back.
Please guide me about likely diagnosis.
My thyroid function were normal during annual in april 2008. On this March 2009, I had T4 level -13.7, T3- 41 and TSH very low. FTI was 5.6 and high. My TPO was more than 1000 and TSH immunoglubin was negative. I am still awaiting report on my RAIU. My doctor is considering Hashitoxicosis vs. Graves disease. I am 43 and had permanent sterilization 5 years back.
Please guide me about likely diagnosis.
it sounds like you have exactly what i have. i initially was hyperT, then moved into hypoT. i was diagnosed last year at about this time with thyroiditis. i had a tsh of .004, and high free t3, and high antithyroglobulin. i continued to get my tsh and ft4 checked, and in july 2008 i moved into hypothyroidism with a tsh of 56. i've been on 112mcg of synthroid since and have been on the thyroid roller coaster ever since.
you'll have to have your tsh, ft3, and ft4 checked regularly to see if you need synthroid. your doc may wait and see what these values do, and if the tsh gets too high, they'll put you on synthroid. or your thyroid will heal and start working properly soon. hopefully that will be the scenario for you. regardless, you'll bave to deal with the hypoT issues now. hang in there. it'll take time, but it'll get better.
you'll have to have your tsh, ft3, and ft4 checked regularly to see if you need synthroid. your doc may wait and see what these values do, and if the tsh gets too high, they'll put you on synthroid. or your thyroid will heal and start working properly soon. hopefully that will be the scenario for you. regardless, you'll bave to deal with the hypoT issues now. hang in there. it'll take time, but it'll get better.
I have my RAIU result now shows o.04% or very low uptake. Also my pulse is now 60/min from earlier 72/min. I now have got menses with large clots.
I don't see a high Ft3 test done on this member. Only a T3 - so to decifer the T3 toxicosis a Free T3 level would need to be done. Correct? Nor do I see any TSI / Graves testing.
unfortunately, you have to wait to get the raiu results. i was in the same situation as you...low tsh, high ft3. it's hard to distinguish between hashi and graves in this situation. i initially had t3 thyrotoxicosis then eventually moved into hypothyroidism. the raiu (very low uptake) is what gave the definitive diagnosis.
your doc is definitely running the right tests. you have the blood work piece of the puzzle. the raiu should give you a complete picture of your diagnosis. i know waiting is tough, but that's where you are right now.
your doc is definitely running the right tests. you have the blood work piece of the puzzle. the raiu should give you a complete picture of your diagnosis. i know waiting is tough, but that's where you are right now.
You should push for more testing then. Your lab clearly shows Hashimoto on the antibody tests. the thing that mostly happens with Hashimoto is most people do come out "normal" on a TSH with high antibodies and their doctor dismisses all thyroid functions as normal. - . BUT most still experience hypo symptoms while these antibodies are rearing up.
Really the FTI you reference too is useless. I wouldn't even put that into prespective.
Also most find that looking into the FREE T3 ( Not the T3) and tweeking that level up to the high points of the reference range can rid them - sometimes entirely - on all hypo symptoms whether Hashimoto or not.
Trick is to find a doctor that will concentrate on looking at the Free levels then only looking at a TSH.
Really the FTI you reference too is useless. I wouldn't even put that into prespective.
Also most find that looking into the FREE T3 ( Not the T3) and tweeking that level up to the high points of the reference range can rid them - sometimes entirely - on all hypo symptoms whether Hashimoto or not.
Trick is to find a doctor that will concentrate on looking at the Free levels then only looking at a TSH.
I am mainly worried for muscle ache and muscle spasm which is affecting my sleep and work.
I think your doctor is giving you a good possibility here. Why are you questioning them?
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