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Avatar universal

High TSH and Thyroid Peroxidase Antibodies, but normal T3 and T4

I'm a little confused about my test results, and I'm hoping that I can get some insight from the community.
Here are my results

TSH is 5.76
FT3 is 3.0
FT4 is 1.1
Thyroblobulin Auto Antibody is 27.9
Thyroid Peroxidase Auto Antibody is 453
Thyroid is enlarged, but I hadn't noticed until my Dr. discovered this (and sent me for an ultrasound to confirm).

What does this mean?  Since my T3 and T4 are in normal range, putting me on replacement therapy wouldn't really do anything would it?
Also, my blood test revealed a vitamin D deficiency.  If was 17.
Best Answer
Avatar universal
You really do need to supplement your Vitamin D level to get it up over the middle of its range.  

Beyond that, a test result like yours, for TPO ab, almost always means Hashimoto's Thyroiditis, which is the most common cause for diagnosed hypothyroidism.  If I assume that the ranges for your Free T3 and Free T4 are similar to those seen so often, then your Free T3 and Free T4 are within the so-called "normal' range, but your Free T3 is in the lower half of its range, which frequently is accompanied by hypothyroid symptoms.   The range is too broad to really be a functional range, due to the erroneous way it was established.  Your Free T4 would be considered as adequate.  

So first, please post the reference ranges for the Free T3 and Free T4, as shown on the lab report.  Second, please tell us about any symptoms you are having.  Third, I suggest that when you go for testing again, you should also request to be tested for Vitamin B12, and ferritin.  Even though men are usually assumed to have adequate iron levels, ferritin is so important for someone that is treated for hypothyroidism, you need to make sure your level is adequate.

  



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Avatar universal
Here were the results of my additional blood tests.  These seem to be in normal ranges.

FERRITIN - 101 ng/ml
VITAMIN B12 - 413 pg/ml
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Avatar universal
Just because thyroid test results are in the so-called "normal" ranges does not mean that is adequate for YOU.  First, everyone is different and react differently to thyroid hormone levels.  Second, the ranges are far too broad due to the erroneous way they were established.  As a result, many members, myself included, say that relief from hypo symptoms required Free T3 in the upper third of its range and Free T4 around the middle of its range.  

So, with Hashi's as the probable cause it is only a matter  of time until your levels drop further and you start having even more severe hypo symptoms.  Many doctors like to wait until a Hashi's patient gets to that situation before prescribing thyroid meds.  Other doctors like to start earlier in order to try and maintain the patient's thyroid hormone levels and prevent symptoms.  

A good thyroid doctor will treat a hypo patient clinically by testing and adjusting Free T3 and Free T4 as necessary to relieve symptoms, without being constrained by resultant TSH levels.  You can get some good insight into clinical treatment from this letter written by a good thyroid doctor for patients that he sometimes consults with after initial tests and evaluation.  The letter is then sent to the participating doctor of the patient to help guide treatment.  In the letter, please note the statement, "the ultimate
criterion for dose adjustment must always be the clinical response of the patient."

http://hormonerestoration.com/files/ThyroidPMD.pdf

So you need to take care of the Vitamin D problem.  You need to make sure your B12 and ferritin levels are well up in their ranges.  And you need to find out if your doctor is going to be willing to treat you clinically as described above.  If not, then you will need to find a good thyroid doctor that will do so.
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Avatar universal
Your TSH is above the new limit 3.3 and even above old limit 5.0
So this condition can be considered as subclinical hypo (rare among the males)
Helpful - 0
Avatar universal
Thanks for the additional info.

The ranges on the lab report are as follows.
FT3 - (2.3-4.2) pg/ml  Mine was 3.0
FT4 - (0.7-1.5) pg/dl   Mine was 1.1

I'm not sure about the symptoms.  Once the Dr. did the initial test for TSH, and said that I probably had Hashimoto's Thyroiditis, I did some research, and in hindsight, have some of the symptoms.  Inability to concentrate, callused heels, varying emotional levels (depression/mania/anger), low energy.
I never noticed the inflammation of the thyroid though.

Again, thanks for the info.
Helpful - 0

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