Aa
Aa
A
A
A
Close
Avatar universal

Is it okay to double up Tirosint one day a week?

Hi,

I have been on Tirosint 88 which will be increased to Tirosint 100.

I have two months worth of Tirosint 88 at home which I can toss or take an extra of one day a week to bring my dose to 705 a week. Just 5 above what it would be at 100 daily. Is it a bad idea to double up once a week? Is it too much or not good for your body?

I also have two months worth of Levoxyl 100 at home. My old script before asking to switch to Tirosint. Can I take those in lieu of Tirosint 100 just to finish them up?

I would like to save the money and not toss four months worth of scripts, but not at the expense of my health. I don't know enough to make a decision and have been asking my doctor so many questions via email that I don't want to tax his patience at the moment.

Thanks
Best Answer
Avatar universal
The active ingredient in Levoxyl and Tirosint is exactly the same, T4.  However, absorption of Tirosint is supposed to be much higher, and of course, Tirosint doesn't have the fillers that tablets have, which some people are sensitive to.

If we accept the theory that Tirosint is more readily absorbed, then 100 Tirosint would get considerably more T4 into your bloodstream than 100 Levoxyl.  So, I wouldn't switch from Tirosint because that's just going to add one more variable into the mix.  

If you're not sensitive to meds, you can add in an extra Tirosint once a week.  Doctors often prescribe it that way to achieve non-standard doses.  

If I were you, though, I'd tuck them away somewhere in case your 100 mcg dose doesn't work out and they might become useful again.  It's going to take a loooong time (@ 15 months) to use up two months worth (60) only taking one extra a week.  By then, the Tirosint will probably be beyond its expiration date.  I don't think it's worth it to throw another variable into the works.
10 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Hi Barb,

Thanks for your comment.

Good point on the expiration date.

You'll be happy to know that my doctor's agreed to increase my Tirosint to 100 and is aware that I've been recently taking additional Cytomel (although we didn't specifically talk about increasing Cytomel, I told him I have).

So, I'm not self medicating :)

I did  email him all these questions. Greatly confused him so we went back and forth. I was afraid of trying his patience.

Thank you so much - I always appreciate your advice!
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Just because the expiration date has passed on a medication, doesn't mean that it won't still work.  

This is not to say that I recommend self medicating, because I don't......
Helpful - 0
Avatar universal
Hi Goolarra,

In the end, I agree with you and have started on Tirosint 100s. I'll put the 88 aside until they expire or I need to use them and I'm forgetting about Levoxyl - shame as I have so much of it, but I agree with you. Thank you so much for your help in deciding.

I've not found any interactions so I'll take one soon and as needed until we've moved from this apartment and/or my symptoms have improved.

Finally out of questions here - until next time :)

Thanks so much for all your help. It's been a trying time and I appreciate it.
Helpful - 0
Avatar universal
I really don't like the idea of taking the Levoxyl.  If you believe the claims that Tirosint is much more readily absorbed (I think I've read up to 40% better absorption), then you could be decreasing significantly moving from 88 Tirosint to 100 Levoxyl.  It's not worth it...

I have no idea about Fluconozole.  We live in the desert, so molds and yeasts aren't a big item.  You might go to one of the drug interaction websites and check out what they have to say.
Helpful - 0
Avatar universal
Hi Goolarra,

Thanks for your reply.

Okay, I will continue to take Cytomel until I start feeling better or am reaching maybe the four week mark of increased Tirosint (100). At that point I might drop the additional Cytomel (5) or cut back to 2.5 bringing me to Cytomel 12.5 total for the day.

I decided to just go ahead and start on Tirosint 100 and not try and use up what I have. Unfortunately, my doctor is now aware that I have additional Tirosint 88 and Levoxyl 100 lying around and might be more cautions with his refills? I also thourouly confused him and in the end he recommended taking the Levoxyls instead of adding an additional 88 of Tirosint once a week.

I also had the Levoxyls filled 13 and 14 months ago so according to the script bottles they're expired. This may or may not be true, but I have no way of knowing for sure. Tirosint expiration dates are written right on the box.

I've decided I'm going to pay my one Tirosint 100 refill out of pocket. It's only $5 more than what insurance covers for it (can you believe it!) and ask him to call in a new prescription.

Thanks for the tip with insurance, I'm going to do that. The office person is so bad at calling in scripts that if I counted on here I would be without for several days several times. I hate talking to her when I call for appointments or have to ask her for anything. I always feel like a nuisance, annoyed and stressed! Last time I had to talk to her to try and schedule and appointment - I cried as soon as I got off the phone. I'm so unable to deal with stress right now - I hope that changes with dose increase.

I've been taking 4 capsules of Magnesium Citrate before bed. I only did that for a few nights, but have stopped doing so since things seem to be moving again.

I've been feeling especially sh#@^ since a large leak into my temporary rental last week. Different symptoms than thyroid like sinus problems, goopy eyes, pins and needles, (except maybe headache and nausea are due to copper supplements?) rather than mold. I don't mean "black mold" or anything like that, but I have a yeast reaction (not vaginal yeast infection) when in a high mold environment according to my (mainstream) allergist and according to blood work by my former (mainstream) doctor. So I'm feeling especially sh^$# and will have to take Fluconozole until we move into another unit on Sunday. I'm worried that building management will play us around and worrying doesn't help anything!

Do you happen to known how Fluconozole affects hashi/hypo?

Goodness the questions (and problems) never seem to end. Sorry :)
Helpful - 0
Avatar universal
Your FT3 is still very low...if it were me, I wouldn't cut back on it.  It's going to take the added T4 a while to kick in, and even then, you might still need the T3 you've been taking.

If you tolerate taking one extra Tirosint a week well, IMO (forget the humble cr@p!), I don't see any reason not to take it that way.  I'd find that much more acceptable than mixing Tirosint and Levoxyl.  Of course, another approach might be to go ahead and take your 100s now and save the 88s for if/when your doctor wants to cut you back again.  Why play with the 88s now when it might never be necessary?

I stockpile, too, and I've discovered that my pharmacy will refill scripts up to a week before they're actually due.  So, I refill them consistently early, and I have a couple of months ahead at this point.

How much magnesium do you take?    
Helpful - 0
Avatar universal
ROFL, ROFL, ROFL

As I read your reply I thought "goodness my posts are so confusing!" and they are - I'm right there with you :)

I did end up doubling this morning and picked up a new script for Triosint 100.

I just wanted to use up old Levoxyl 100. It was my script before my asking to switch to Tirosint. Although, I had no known reaction to the fillers, I didn't want them.

I also wanted to stockpile Tirosint 100 just in case my doctor can't ignore my supressed TSH, despite low FT3/FT4. He's gone back and forth with me, but might be coming round to the importance of FT3/FT4. He was wise enough to prescribe Cytomel where my former doctor refused. He got me better, then reduced my dose and is now letting me go back up again. You know the story ;)

Thank you so much for your input.

Another question. Should I continue with my Cytomel increase? Until I start feeling better? I increased (on my own) by 5 taken right before bed and slept well for the five nights that I did this. Last night I didn't take an additional Cytomel 5 because I was planning on doubling up Tirosint 88. I had an awful sleep. Woke up so many times including waking up to urinate twice.

I've also taken magnesium citrate the past two nights and I'm still constipated! Having other issues too like muscle aches etc.

Thanks again
Helpful - 0
Avatar universal
Sorry, just realized I'm totally out of my mind!  It's a symptom of hypo!  LOL

You'd be taking eight of those 88s in a week, not just one.  You'd use them up in less than two months.  However, I'd still limit the variables.
Helpful - 0
Avatar universal
So I emailed my doctor who told me to break Tirosint 88 in half and spread it though out a week. Problem is that Tirosint is a gel cap - guess he didn't know that. So, I replied telling him so and asking about Levoxyl. I've not heard back yet.

But, this morning I took a double dose of Tirosint 88 and will take rest as usual for the rest of the week. Then do the same next week and until I finish those.

I feel really bad today from having had wine last night so it probably wasn't the best day to double up and watch for symptoms, but it's done now.

If anyone has an input or reason's why I should double up once a week or take a different brand of T4 (same dose). Please let me know cause I'm feeling very unsure about what I'm doing.

Thanks
Helpful - 0
Have an Answer?

You are reading content posted in the Thyroid Disorders Community

Top Thyroid Answerers
649848 tn?1534633700
FL
Avatar universal
MI
1756321 tn?1547095325
Queensland, Australia
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
We tapped the CDC for information on what you need to know about radiation exposure
Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.