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Levothyroxine and Exercise

I take levothyroxine 1/2 hour before my early morning run and  have noticed sometimes heart disturbances in the later in the day... I am not sure if levothyroxine is too blame or should I wait 1 hour before doing my running?

Currently take 150mg x3 and 100mg x 4 per week and TSH 0.18

Have you experience the same thing?

I'm 43 and don't want to damage my heart!
Best Answer
Avatar universal
I have done a lot of searching on this particular issue without finding a lot to go on.  I have found some information suggesting that with a low percentage of hypo patients on T4 meds there was a risk of atrial fibrillation associated with their suppressed TSH level, Why this would be I don't yet understand, since I haven't found any evidence that TSH directly affects heart function.  

I have also seen some study data suggesting that TSH was predominantly correlated with FT4 levels, much more so than FT3 levels.  We also know that patients on significant doses of T4 frequently have suppressed TSH levels.  That does not mean you have become hyper, unless accompanied with hyper symptoms and excessive levels of FT3 and FT4.   And I have seen scientific study data that showed that Ft3 correlated best with hypo symptoms, while FT4 and TSH did not correlate very well at all.

All this has made me stop and think about whether it might be best to rethink our medication practices.  Instead of T4 meds, perhaps we'd be better served by taking a combo, desiccated type, or even separate T4 and T3 meds, to be able to reach adequate FT3 levels to relieve symptoms, without elevating FT4 to much.  

Sorry to be unable to present this as anything other than just my own thoughts at this point.  Of course there are many other factors that can be related to your concern, but since the usual  response to a situation like yours would be for your doctor to reduce your meds, regardless of the effect on hypo symptoms, I think you will eventually need to consider if there are other possible alternatives to reducing your T4 meds and adversely affecting symptoms.    

You might be interested to know that because of these questions, I am currently in the process of reducing my FT4 level, while maintaining my FT3 level high enough to relieve symptoms.  My rationale for this is:  Why do I need for FT4 to be high in the range (thus driving my TSH to .05), if I can take Cytomel adequate to keep my FT3 in the upper part of its range?  I think it is worthwhile finding out.
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Avatar universal
To me, your FT4 result combined with the heart disturbance you mention, confirms that your current meds need to be reduced.  I am somewhat surprised that your doctor has not reacted to the FT4 result.  At any rate, I think you need to discuss this with him and agree on a plan to reduce meds to get your FT4 back to the midpoint of the range.  As you reduce your T4 med, if hypo symptoms start to appear,  you can maybe get prior agreement with the doctor to prescribe a T3 med to address those symptoms.  
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Avatar universal
Thanks for your reply, here are my reference ranges

Free T4 -  24.0 (10.0 -20.0) H
TSH     -     0.18 (0.30- 4.00)

Unfortunately I don't have my T3 result.
And we don't have combo T4/T3 meds here in NZ.. So we have to take them separately.

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Avatar universal
Here in the US, we have available some combo T4/T3 types and then there is also the option of taking a T3 med, like Cytomel, along with T4 meds.  

T3 containing meds have a half life of less than a day, compared to about 7 days for T4.  So typically it is recommended to split the daily dose of T3 meds in half and take in morning and  early afternoon.  That helps even out the effect of the T3 and also helps prevent any difficulties with going to sleep at night.

Could you please also post your thyroid test results and reference ranges shown on the lab report.  That would be helpful as an indicator of your current status.  

.
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Avatar universal
Thanks for your reply..

It is hard to describe the heart disturbances, as I guess its sensation of your hear beating.
Anyway its uncomfortable when it happens and no my heart isn't racing as I have a 60-64 beats normal heat rate..
And I haven't experienced shortness of breath
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Avatar universal
Thanks for your thoughts..
I have forgotten that I can take a combo meds T3 and T4 as opposed to T4..
But I am unsure whether my doc is aware of it.. It sounds like the better way to go..
Do you have take the T3 at separate times? or with your T4 medication?

Currently take Goldshield meds..
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
What type of "disturbances" are you having later in the day?

You only need to wait 1 hour before eating; I don't think exercise matters much.

I do know that when I was still hypo, I had symptoms of being hyper - heart palpitations, seemingly rapid heart rate/pounding (but really normal), shortness of breath, etc. Since I've gotten my levels to a point that's good for me, these symptoms have pretty much been alleviated.  
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