I started taking thyroid hormone levothyroxine 50mcg (smallest dose) on March 15, almost a two months now. I noticed about 4 weeks after I started taking it that my acne was beginning to flare up. I had it under control for many months by that point, and I'm trying to figure out if the levothyroxine is the cause. My endocrinologist told me that my thyroid function was normal without the medication but I am taking it because I have nodules (the medication slows down their growth.) Which leads me to believe that I have an overproduction of hormones in my system. I am also on the birth control pill Kariva. I was told that they would not interfere with each other, however something is not right and I was just wondering if anyone out there could help me out. I can't get back to the endocrinologist for another 4 months for my next test, so I did not want to stop the medication. Does anyone know how long it stays in your body...I was considering not taking it for a few weeks just to see if this cleared up.