I have taken thyroxin at night only to find I wake up during the night with wild nightmares so I went back to taking it in the morning and have no problems with it.
After a while the body gets used to some of the side effects and they either 'lessen' or go away.
Persevere with the side effects...they are short lived.
I also take mine around 5.30am with a coffee (even though they say not too) and have had no ill effects.
When I go for bloods at 8am in the morning, I have to eat a sandwich beforehand as my blood sugar goes low and without it, feel I am going to faint when blood is taken.
I then take my thyroxin straight after in the Pathology waiting room....probably 15 mins after bloods and have had no effects from doing this too.
Stick to the same routine consistantly and you will be fine.
I take Armour, which is natural T4/T3. I take it at night at 10pm after 2 hours of not eating so it is well absorbed. I have absolutely no problem falling and staying asleep. I too was told that naturally your thyroid hormone peaks at night so I am just mimicking what my body would do naturally. The 'take it in the morning' is for convenience so you can take it on an empty stomach. But then you have to wait at least 1/2 hour before being able to eat. I don't have sugar problems but I can't go without eating for that long after I wake up. Once again taking it at night does not interfere with my sleep at all. Those of you who said you won't be able to sleep at night, are you talking from personal experience or just from what you think or have heard? I had to change endos just because my old one refused to prescrive Armour (the natural one). I was not doing well anymore on Synthroid. I alwasy had that 'I'm just not feeling totally well' feeling. Armour has made a big difference to me. And I had not had any of the issues that are floating around about it.
A research reported in the journal Clinical Endocrinology found that taking the same dose of levothyroxine (i.e., Synthroid) at bedtime, as compared to first thing in the morning, might be better.
That's good news for me, too.
http://thyroid.about.com/od/thyroiddrugstreatments/a/bedtime.htm
I'm having the same problem Rachel. Thats why I cam on here, to see if anyone else was going through this. Mine is Very strange (I just started it 3 days ago) About 33min, like clock work after taking the med, I get dizzy, like bad vertigo. Then about 30 min after that (After I have eaten something) I get really groggy and have to go lay down. I will sleep for 4-5 hours and my husband came and woke me up, I still am groggy the rest of the day, it seems strange, but my husband could tell the first day that it helped, he said my color looked alot better(I've been pale since I felt sick) and he said my eyes weren't near as puffy as they had been, so it is working, I just don't like the effects its doing to fix the problem..
I've found that I have a terrible time staying awake in the morning. Not right away when I get up, but about an hour after. I have to pull of the road and close my eyes for 10 minutes almost every day on my way to work. I take the meds as soon as I wake up. Although many of my other hypo symptoms have improved since I started taking the synthroid, this particular symptom seemed to develop only after I started on the meds. I've wondered if it's possible that it is a reaction to the synthroid. Anyone else ever feel this way from taking it?
FYI, in the beginning of my treatment I was also taking prevacid (a proton pump inhibitor) for gerd and heatburn first thing in the morning (and I also wanted to eat shortly after taking the prevacid), so my endo MD told me to take the synthroid at night! It must be taken on an empty stomach, so I take it three hours after lunch!! Then I wait at least 30 minute after taking synthroid until I eat something, I usually try to wait an hour. I've also taken it at bedtime when my dining/eat schedule strayed from my normal routine and I was able to sleep normally, no problem.