I do B12 shots weekly, and it has made a huge difference! It also gets rid of the neuropathy I still have in my hands and feet.
Usually those 2 supplements are good for thyroid patients. Our bodies are robbed of them when this disease is with us.
Another is the Vit D
Citrate is the best form to take due to absorption.
My b12 was low in all my blood tests. I get a b12 shot every time I stop by my dr. They are painless but honestly I can't tell they do anything.
Also I was taking multivitamins that I bought at target. They were one a day for men. Then I read on a thyroid web site not to take these, and to go to a vitamin store and buy a good vitamin. I bought a supped up vitamin that has tons of d and b12 in it. Also taking a c, and an extra hit of d.
The vitamins I bought you take 3 times a day so it is absorbed and not peed out.
I had my B12 tested prior to bing diagnosed, around 15 years ago. I had zero levels! I was exhausted and KNEW my thyroid was off, but couldn't get a doctor to listen. BUT he says, B12 was so low it was becoming dangerous. That was a stunner to me! I was a part vegetarian back then. Years later when tested again, I was still low. I scratched my head. Bulked up on all the goodies that give you B12 and still it was low.
I believe it was a symptom of having the start of my Hashimoto's and (at that time) my severe hypothyroidism.
Only in the past few years did I change from cow's milk to Soy milk and within two weeks asking to be retested, my B12 levels were through the roof! Couldn't believe it. Now I know most people will jump on me and say not to have soy, but pffft. If for me nothing else works for B12 (even taking a capsule of it for years!) then I will stay with it. Besides I only have it in a cup of tea and only a few times a day.
I try to avoid multi-vitamins as the logic is, our bodies only absorb around 5% of it.
BUT the issue for me is still ongoing fatigue etc. So having super wonderful B12 levels now, (we need it for so many things!) is great for my body, but I seriously would never have known any difference if I was never tested.
Put it this way, taking it can't hurt!
I've only been tested once for everything except B12 and because I have pernicious anemia, that is checked on a regular basis.
I can tell you, from experience that just because B12 levels are "in range", doesn't mean you don't need to supplement. When I was diagnosed with pernicious anemia 4 yrs ago (for the second time), my B12 levels were slightly above 200 (range 200 - 1100). After being on monthly shots for a year, my levels were still only up to about 500, so my shots were increased to every 2 weeks. My latest levels (after 3 1/2 yrs) were just over 700. As my shots were increased, I felt better, but not good enough to even get through a day without crashing. I am now on weekly shots and can tell a world of difference...... I can also tell when the week is up and it's time for another shot. So, the 200, 500, and 700 were all "in range", but none of them optimal. I am due to be tested again in early Feb. so will see what my levels are then.
For B12 supplementation, I've tried tablets, capsules, liquid, sub lingual and injections; injections are the only form that makes a noticeable difference, though I could tell a slight difference with the sub lingual after taking them for about a month. Even did sub lingual with my monthly shots for some months and couldn't tell a difference.
The main others that I can tell a lot of difference from is selenium and magnesium. I was deficient in both.
I do not take a multi because, like you, I feel that they can't really get that much stuff into one pill and I've never found one that I can tell a difference with. So, yes, I end up taking a handful of pills every day, actually, supposed to take the vitamins/minerals twice a day (don't usually); and these are over and above my 2 thyroid and 2 blood pressure med(s).........