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Help diphering lab results
hello all, quick break down: Hashimotos diag 2013, Rx: Levothyroxine/Synthroid .25 to .50 Just increased 10/23/15 to .75. Other issues IBS, Prediabetic....Ultimately given my birth story I think I was born with the condition just diagnosed in my late 30's
Thank You so much for your grace and assistance. these labs are from 4/25/15 I have new labs for TSH, T4, and T3 on 10/23/15 (awaiting results)
These are from a yearly physical from which I did a gamete of blood work. The Dr said my iron stores was fine but I don't really believe it, I have always been anemic.
Iron and Total Iron binding capacity
Iron total: 70 MCG/DL: 40-190
TIBC: 399 MCG/DL: 250-450
Saturation: 18 Percent: 11-50
Ferritin: 13 MCG/DL 10-154
TSH: 2.85 MIU/L 0.40-4.50
T4, Free: 1.1 NG/DL 0.8-1.8
T3, Free: 3.0 PG/ML 2.3-4.2
Vitamin B12, Serum: 794 PG/ML 200-1100
Vitamin D Total: 25 NG/DL 2-45
ANA Screen: Negative
Mitochondrial AB W/RFX Titer: Less than 1:20
Thyroid Peroxidase Antibodies: 324 IU/ML <9
Testorerone, Total: 26 NG/DL 2-45
Progesterone <0.5
Thank You so much for your grace and assistance. these labs are from 4/25/15 I have new labs for TSH, T4, and T3 on 10/23/15 (awaiting results)
These are from a yearly physical from which I did a gamete of blood work. The Dr said my iron stores was fine but I don't really believe it, I have always been anemic.
Iron and Total Iron binding capacity
Iron total: 70 MCG/DL: 40-190
TIBC: 399 MCG/DL: 250-450
Saturation: 18 Percent: 11-50
Ferritin: 13 MCG/DL 10-154
TSH: 2.85 MIU/L 0.40-4.50
T4, Free: 1.1 NG/DL 0.8-1.8
T3, Free: 3.0 PG/ML 2.3-4.2
Vitamin B12, Serum: 794 PG/ML 200-1100
Vitamin D Total: 25 NG/DL 2-45
ANA Screen: Negative
Mitochondrial AB W/RFX Titer: Less than 1:20
Thyroid Peroxidase Antibodies: 324 IU/ML <9
Testorerone, Total: 26 NG/DL 2-45
Progesterone <0.5
My mom said I was treated inter-utero with mass amounts of antibiotics about 6 months into the pregnancy. When she delivered @ 10 months, I was still sick. I later developed spinal meningitis's at 6 months and was deathly sick. Growing up I was ok, but I can remember bad bouts of stomach pain and inflammation in my face (it would come and go) Now in my later 30's the systems have really exacerbated. I'm beginning to think if the doc's really don't know much now about the endocrine/thyroid what did they know then. I won't complain (nothing short of a miracle) they did save my life as it was determined I would be blind, deaf and mentally impaired, up the last 15 years I've lived a pretty healthy life.
Thank You...I guess my next thing is to look into diet and supplements after I look at my next two blood work orders.
Hair loss is a common symptom of being undermedicated for hypothyroidisim and also a symptom of low ferrtiin.
Regarding the iron question, note this info from a reliable source.
Iron deficiency
"Iron deficiency is shown to significantly reduce T4 to T3 conversion, increase reverse T3 levels, and block the thermogenic (metabolism boosting) properties of thyroid hormone (238-242). Thus, iron deficiency, as indicated by an iron saturation below 25 or a ferritin below 70, will result in diminished intracellular T3 levels. Additionally, T4 should not be considered adequate thyroid replacement if iron deficiency is present."
Next is that your last set of tests show a Free T4 level that was too low in the range. It should be middle of the range, 1.3 or somewhat above. Also your Free T3 was at 3 which is only about 37% of its range, when it should be in the upper half of its range, as needed to relieve symptoms. I seriously doubt that the last increase in your T4 med is going to be enough. We'll see how your latest test results look.
Your B12 is not bad. Recommended level is upper part of its range. Your D is too low by far. Should be more like 55-60.
TSH is basically a useless test when already taking thyroid med. Frequently when you get up to adequate med dosages, the TSH becomes suppressed below range. That does not mean hyperthyroidism unless there are hyper symptoms due to excessive levels of Free T4 and Free T3. I mention that just to alert you should it occur and the doctor decide you must be on too much med.
Iron deficiency
"Iron deficiency is shown to significantly reduce T4 to T3 conversion, increase reverse T3 levels, and block the thermogenic (metabolism boosting) properties of thyroid hormone (238-242). Thus, iron deficiency, as indicated by an iron saturation below 25 or a ferritin below 70, will result in diminished intracellular T3 levels. Additionally, T4 should not be considered adequate thyroid replacement if iron deficiency is present."
Next is that your last set of tests show a Free T4 level that was too low in the range. It should be middle of the range, 1.3 or somewhat above. Also your Free T3 was at 3 which is only about 37% of its range, when it should be in the upper half of its range, as needed to relieve symptoms. I seriously doubt that the last increase in your T4 med is going to be enough. We'll see how your latest test results look.
Your B12 is not bad. Recommended level is upper part of its range. Your D is too low by far. Should be more like 55-60.
TSH is basically a useless test when already taking thyroid med. Frequently when you get up to adequate med dosages, the TSH becomes suppressed below range. That does not mean hyperthyroidism unless there are hyper symptoms due to excessive levels of Free T4 and Free T3. I mention that just to alert you should it occur and the doctor decide you must be on too much med.
1 Comments
Wow so the current upped dose is still low! funny thing is when I took the .75 that same day I felt bad...got that foggy headache and my equilibrium was off.
Before commenting on the lab test results, please tell us about any symptoms you are having. Symptoms are a better indicator than lab tests.
3 Comments
well before the dx I was feeling like I was dying, 12-13 hours of sleep, breast tenderness life i had a fire on my chest. forgetting stuff even my own number. I just thought I was stressed. I had headaches daily. Fast forward with the drugs...I have more energy but not totally well. I am attempting to change my diet.
simply put, my whole body hurt daily and I was never fully rested after hours of sleep. I had typical cold feet and hands, fast heart beat.
the more I think about, My hair is and still disappearing, on one eye all the lashes fell off just recently.
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To begin with, your April thyroid labs were somewhat short of the levels we, typically, recommend... Rule of thumb (where most of us feel best) is for FT4 to be about mid range; yours was only at 30%. Rule of thumb for FT3 is upper half to upper third of its range and yours was only at 37% of its range. You had quite a ways to go with both of those...
You were quite right not to believe your doctor about the iron stores... Your ferritin level was pretty dismal at only 13. Optimal level is around 60-70...
Your vitamin D was also dismal at only 25... optimal is around 55.
Both iron and vitamin D are necessary for the proper metabolism of thyroid hormones.
Your TPOab confirms Hashimoto's.
What condition do you think you were born with?