Tsh levels and prednisone

[Maharet35]

Can prednisone drop tsh levels in the blood?  Started my dose of 20 mg three times a day.  The next day went in to do labs and my tsh is .25.  Just wondering if I have a thyroid prob or not

[gimel]

Yes, prednisone would cause TSH to drop.  There is a scientific study that concluded that. I was surprised that even in the relatively short time there was no corresponding change in T4 and T3.  I expect they would also be affected eventually, by the drop in TSH.  

http://www.ncbi.nlm.nih.gov/pubmed/114570

Abstract

The effect of exogenous prednisone on serum thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3) concentrations was investigated in four patients with non-functioning thyroid glands receiving T4 replacement therapy. Orally administered prednisone, in a dose of 20 mg each day for nine days, resulted in a significant decrease in mean serum TSH levels (p less than 0.01) without significant changes in levels of serum T4, T3, and thyroxine binding globulin (TBG). These findings suggest an inhibitory action of relatively low pharmacologic doses of prednisone on TSH release without changes in circulating thyroid hormone concentrations or inhibition of the peripheral conversion of T4 to T3.

[Maharet35]

Would only 60mg prednisone cause it to drp