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What is the difference?? Levo/Synthroid

What is the difference between Levo & Synthroid? I was on 150mcg of Levo, but my new Endo swithced it to 175mcg Synthroid. My endo does not for some reason like Levothyroxine.

I have been on Levo for 18yrs, NEVER, had issues with it. Just curious.
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Avatar universal
It's kind of odd that your TSH went from 2.47 to 13.8 without a major change in your symptoms (if I'm interpreting correctly that bone pain is the only really new symptom?).  

I have to tell you that a couple of things your endo is doing don't impress me favorably.  After an increase from 125 to 150, she really should have done labs before increasing your meds again...she has no idea what the first increase has done.  Furthermore, she hasn't even seen your FT3 and FT4, and I'm sure you've been around long enough to know that I think that's a recipe for disaster.  

Between lack of testing and your calcium levels, I don't have any idea why she's waiting over two months to do more labwork.  

Many things can influence TSH.  I have a pituitary issue, and my TSH hovers around 20, but my FT3 and FT4 are good, and I'm symptom-free.

I don't know, Totie, but my guess is this endo might not be a keeper.      
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Avatar universal
I am extremely under weight; have been for the last 3 yrs.

I lost two pounds in two weeks without trying...I eat like a pig BUT never feel full.

The only symptom I told her I had issues with was bone pain. I suffer from insomnia & have since my thyroid storms 18yrs ago. I do get night sweats & have cold intolerance, but that is about it. I had fatigue at one time but since they put me 150 I have gotten a bit better at that. However, fatigue for me could be doue to lack of sleep. (insomnia).

This was my first time seeing this Endo, I have always been under the care of my Primary, but when the TSH level rose he sent me to her.

She has yet to do lab work & won't until Feb 16 when she also looks into parathyroidism. My calcium levles were 10.2 & 10.4. She also prescribed Vit D 50000000 for tweleve weeks.

I did not go to her to complain as I am used to most of the symptoms; I was sent to her due to TSH. I don't have any other labs but that & my primary ran that one.

She did not even run a TSH to see how I did on six weeks of 150mcg, before I was on 125mcg for about 5 yrs.

The only bother symptom I have is BONE PAIN. mainly thighs & legs.
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Avatar universal
Well, the increase would be due to your TSH rising (hopefully, your doctor also tested FT3 and FT4).  However, that doesn't explain the switch to Synthroid from generic.  He could have just raised your dose from 150 generic to 175 generic.

"I am clinically hypo, however if you saw me you would not think it."  Does that mean you don't have any hypo symptoms?  If you don't have hypo symptoms, and your doctor is basing his meds adjustments on TSH only, you may want to discuss the increase with him further...
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Avatar universal
Oh I see.

The switch was made due to my TSH rising to 13.8 from 2.47 a year ago.

I was on 125mcg of Levo, but six weeks ago was upped to 150mcg, & as of yesterday 175mcg, but this time Synthroid.

I am clinically hypo, however if you saw me you would not think it.  I had a TT back in 1994.
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Avatar universal
Levothyroxine is the generic name for the medication.  Synthroid, Levoxyl are brand names of the same medication.

Some doctors, especially endos, it seems are convinced that the brand names are superior to the generic.  Generics can be nmade by any number of manufacturers, and there is no guarantee that the same manufacturer is making your tablets from one refill to the next.  The reason cited for preferring brand names is usually "consistency".  Supposedly, the actual levothyroxine content varies more in the generic.

Like you, I've been on generic, Synthroid and Levoxyl at one time or another, and I found absolutely no difference among them.  However, my endo is one who doesn't like generic.  He put me on Levoxyl.  You have to chose your battles, I guess, so I'm keeping him happy.

Interestingly enough, after switching to Levoxyl from generic (same dose), my labs actually took a nose dive.  

Is generic really an inferior product, or have the drug reps from the major brand names just done a really good job of defaming their competition?  IDK  Obviously, if you've been on generic for 18 years with no ill effects, the switch seems to be a bit unwarranted.

The only difference in the different brands and the generic is the fillers (inactive ingredients) used.  These vary from manufacturer to manufacturer, even among the brand names.  Some people are allergic or sensitive to some of these fillers, and switching can solve their problems.
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