Hello. Thank you for any answers here. I appreciate it. I am a 33 yo woman, mother of 3 kids. Until 1 year ago, I was a very high energy person. I had lost a great deal of weight after my last child (over 100 pounds) w/o surgery, exercised, worked as a personal trainer, ate very healthily, and weighed low 140-high 130s (5'4".) I began to feel very exhausted all the time. I was given an anti-depressant, which helped a little but not a lot. Upped the dose, changed the med, etc. I was still exhausted. Multiple TSH tests were given, blood sugar, WBC, RBC, etc. Nothing remarkable. Since this issue occurred, I've now gained 40 pounds and feel terrible and exhausted. My TSH is .9 to 1.3. All other tests were fine but potassium was very low 3.3. Also, my GP prescribed me estrogen/proges cream to take 2x a day. Shortly, thereafter I went to an endorcrinologist b/c I just couldn't understand why I felt so horrible. She felt a nodule. A sonogram was done, it was something like 1.7 x 1.2 cm. She did the biopsy yesterday. After she took four samples, I came up from lying down and she became exasperated. My lymph glands became extremely swollen and hard (on the R side), biopsy was on L. She wanted me to go get an ultrasound, but instead I waited in waiting room until swelling went down and went home & iced. I just didn't feel like making a big deal of it. She said that was fine. She also had said last appt that the E2 cream/progest cream was very dangerous and not typically prescribed for a 33 year old woman with irregular periods. (My estrogen & prog levels were very low at point during month it should have been higher.) Here's my question: a) any ideas why my glands swelled up? She said she had never seen that before. b) She commented that the texture of the nodule was the type to be concerned about. What should/should I be worrying about? Thanks for any help.