seeking diagnosis

[parwati]

my wife, 60, begin feeing of thyroid cyst jan.06. went to see doctor at s.g.p.g.i. (lucknow) ultrtasound done. report.-B/L cystic lesion of thyroid gland(large on right side measuring 35 *19cm. and small on left side measuring 8*5mm. with thick fluid in it cause?COLLOID GOITER.
INVESTIGATIN. THYROID PROFILE- 17 NOV. 2005. FREE T3 3.9 PG/ML, FREE T4 1.2NG/DL, RAPID TH 1.0 IU/ML
INVESTIGATION ON 17 FEB.2008 SEUM TOTAL T3 1.31 NG/ML, SERUM TOTAL T4 7.82 GM/DL, SERUM TSH(ULTRASENSITIVE)0.75 U/ML
aspiration done in feb.06 about 15cc. fluid,
next aspiration in feb. 08. cytology report of THYROID fluid -SMEARS FROM CENTRIFUGED DEPOSIT REVEALED MODERATE CELLULARITY.
THERE ARE SOME CLUSTERS OF FOLLICULAR EPITHELIAL CELLS. THESE CELLS ARE SHOWING MILD PLEOMORPHISM WITH ROUND NULEI AND ABUNDANT EOSINOPHILIC CYTOPLASM. BACKGROUND SHOWS FAIR NUMBER OF FOAMY MACROPHAGES. SOME NEUTROPHILLS, FEW MULTINUCLEATED GIANT CELLS. PATCHY COLLOID NEMEROUS RBC'S.
FINDINGS A RE SUGESTIVE OF BENIGN HAEMORRHAGIC CYST OF THYROID GLAND WITHMILD ATYPIA. MOST PROBABLY COLLOID CYST.
SHE HAS HYPERLIPIDI. 7 years back and on atorva 5mg. maintenance dose,
email- ***@****

[parwati]

dear sir, thanks. you have solved my problem.pl.advice what tests are necessary to be done before going for PEI., and about frequency of injections. i will undergo treatment at lucknow seeking there competent THYROID surgeon. for procedure.

[898]

Some patients are requiring more then one injections; so far no drugs are known to treat the cysts.
The correct abbreviation is "PEI".

[parwati]

dear sir, today consulted a general surgeon(spec.oncology). he adviced SUB TOTAL THYROIDECTOMY.as it is about 3 cm., he says PAE will not help.
my wife is now afraid of surgery ,due to some unforseen cmplications during surgery. doctor has also said it is not urgent. we want to ascertain whether surgery can be avoided by taking medicines or go back to lucknow and ask for PAE, as possibility, for cure.thanking you
parwati

[parwati]

dear sir, pl. write PEI injection and ETHENOL inj. are same or not. i forget to write at S.G.P.G.I. LUCKNOW, in 06, they wrote PLAN- SURGERY ,if rapid refilling+ or ETHENOL inj.. till that time no investigations were made. i am still stuck to know about a suitable endocrinologist in mumbai,

[898]

Iodine deficiency causes general enlargement without nodules ;it starts as diffuse goiter in late teens with gland grows up to  2 times normal volume[and sometimes a lot larger then that]; at around 30 years of age the nodules form; by the mid 40's these nodules are starting to produce excess hormones [become HOT], causing toxic multinodular goiter.

[web_diva]

Perhaps Iodine/Iodide deficiency over the years caused this?

[parwati]

dear sir, thanks. yes it is measure in mm.
regards

[898]

One of the cysts is probably 35 by 19 mm, not cm
This is description of the cyst that formed as a result of intrathyroidal hemorrhage;
After blood was coagulated "digested", the blister was filled with colloid;
Such cysts are treated with PEI injection instead of surgery to prevent reoccurrence