In 2004 a goiter was found on an incidental cspine mri. I underwent an ultrasound that showed a 3.7x1.6x1.9cm solid nodule. It was biopsied and it was non malignant. Initially in 2004 I had one lab result that was t3 of 7.6pg/ml, t4 if 2.09ng/dl and a tsh of 0.305. Along with a nuclear medicine study in 2004 that indicated a multinodular goiter. As directed I have seen a endocrinologist once a year and all subsequent thyroid levels have been normal. Recently April 2010, I was sent for another thyroid ultrasound by my primary doctor because she felt like it was time to be imaged again. I had visited her complaining of tiredness that had been lingering. I thought I might have mononucleosis. To make a long story short, the ultrasound noted a heterogenous, predominantly solid appearing mass measuring 2.9x1.3x1.4cm with numerous coarse and microcalcifications within the lesion. No adenopathy seen in jugular chain or supraclavicular region. The radiologist recommended a us guided fine needle biopsy. When I saw my endocrinologist he said that he did not think I needed another biopsy because he had never seen these type lesions turn out to be cancer. My question is since microcalcifications were seen on the new ultrasound, wouldn't a new biopsy be prudent? I understand that most turn out normal. I would appreciate your advice. thanks