Feverish, week and cold

[Frank303]

Hi, I'm 39, eat well (omnivore), smoke, occasionaly drink, no meds or non Rx drugs and I've had some health problems for over 6m. BAck in Feb had burning sensations on my spine, pins and needles in arms and legs. That went then burning eyes (didn;t think it was allergies though maybe CBC says different) w. Went to my Doc in March and he ran some blood tests and told me to call in for the results. I was told everything was normal (he did HIV test too -VE and STIs -VE).  

In May I had Hepish symptoms but tested Hep B immune Hep C neg at 8 months since any poss risk.

Mid June my groin nodes started giving me pain and have not found the cause. They are still painful. At this time I also had fever /chill and some night sweats where I had to wash my pillows as they were soaked. I've had the  recurring fever and night sweats for a few months now though not so bad

August I had severe chest pains and neck pains NHS 24 said to go to A&E. ECG OK no MI enzymes tested so heart is probably OK



I managed to get a printout of them last week (he missed a page) and there were a few test results that said ABNORMAL.

                               Lower Upper 14-Mar-08 22-Aug-08
Ferritin
Serum Ferritin                 20.0 300.0 90.2 N/A
Whole Blood Count
Large Unstained Cells                 LUC 0.05 0.50 0.15 0.20
Monocyte Count                 MONO 0.2 0.8 0.70 0.60
Lymphocyte Count                 LYMPH 1.5 4.0 1.8 3.40 is that jump normal?
Basophil Count                 BASO 0.01 0.10 0.05 0.16**
Eosinophil Count                 EOS 0.1 0.5 0.06 0.1*
Neutrophil Count                 NEUT 1.5 7.0 8 5.7
White Blood Count                 WBC 4 10 10.8** 10.1**
Mean Platelet Volume MPV 7.0 10.4 10.2 11.6**
Platelet Count                 PLT 140 400 246
Mean Corpuscle Haemglobin MCH 27 32 31
Mean Corpusclar Volume MCV 83 98 90
Haematocrit - PCV                 HCT 0.42 0.54 0.43
Red Blood Cell Count                 RBC 5.0 6.0 4.8**
Hb Estimation                 HB 150
GFR Abbreviated MDRD MDRDA >60
Mean Corpuscular Hb Conc. MCHC Icteric -ve
Serum Lipids
Lipaemia Lipaemia -ve
Haemolysis
Free T4 Level                 10 25 16
Thyroid Stim Hormone 0.35 3.30 1.33
Gamma G.T. Level                 4 35 23
Serum Alkaline Phosphatase ALP 45 105 59
                                                ALT 1 40 19
Total Biluribin                 1 22 8
Serum Albumin               37 49 48
Kidney Function
Serum Creatinine               84 116 86
Serum Urea level                3.4 7.0 7.1**
Serum Chloride              98 106 106*
Serum Potassium               3.5 4.9 4.3
Serum Sodium            137 144 138


Anyone able  to interpret these.? I'm not getting much guidance from my GP, I don't know a private Doctor in town and it's December until I can see a private Doctor in London. I'm absolutely shattered at work. Clearly I'm anaemic to some degree high WBC low RBC and having to wear many layers of clothes to keep warm even in the sun. I'm not sure type of anemia though. Hair is graying quite a bit and I'm not under much stress so perhap B12 deficiency?


The last two weeks I've also had a numb left hand, hot spot s on my spine. Tinnitus is whistlin like a kettle and brain fog is leaving me quite confused it's even not making it easy to write this.


Any clues?

[Frank303]

Many thanks and apologies for the delay in responding, been immersing myself in work trying to keep out of  self-DXing  but my Doctor I think is thinking of me as a pest so saving for a private Doctor.

Update
I did have some colonic bleeding usually fresh but on some occasions digested. I was referred to a GI surgeon for a Flexi Sig and had three haemmorhoids rubber-banded. That seems to have cleared up the groin pain to an extent.
Still have nausea a couple of hours after eating but I have a follow up appointment with the GI surgeon early Feb when i will be able to discuss this and he may run a H. Pylori test or check for ulcers.
He said I'm not anaemic as my Haemglobin is OK - I thought anaemia was low red count.

The parasthesia on my smallest two digits is still much the same and not varying with stretching, working overhead or resting. The digits are getting a bit clawed now and since I'm not using the two digits the muscle is wasting, nails in general have gotten far more convex than before.

I think the convexing of my nails is maybe pulmonary as I was a smoker,  also if I breathe in deep I get zaps going to the small two digits. These zaps and ringing in my fingers happen without any stimulus too.
I've to see my GP for a chest x-ray. The private Doctor I saw said low red count and high white count (though both moderate and just out of band probably indicate something about my smoking and the eonosphil count in March could have been a bacterial infection. Someone PMed me on a non medical forum using an alias and said to get a TB test! I find a mate has had TB and no idea where he got it from as he isn't in the main risk groups (not HIV+, not travelled to endemic countries...).

Cardiologist ruled out MI by ECG following stabbing pains in chest, which always give me a jolt. Maybe it's the GI symptoms.

I'll leave the parasthesia until the new year and try and get some swimming exercise in  as it's maybe just compression
My Histo Labs (HLA) have A2, A68, B35 B44,DRB1* 0101 and 0401 (MS, RA), DRB4. Limited alleles checked for.

I tested for HIV and Hep B&C (Hep B immune since the booster) way beyond the window period,

[Dr. Kokil Mathur]

Hi
Thanks for keeping me posted.

No, Chlamydia is not a known cause of Gullian Barre (GB), however the exact cause of GB is not known. “What causes GBS is not known; however, in about half of all cases the onset of the syndrome follows a viral or bacterial infection, such as the following:

Campylobacteriosis (usually from eating undercooked poultry)
Flu (influenza), common cold
Gastrointestinal viral infection
HIV
Infectious mononucleosis
Porphyria (rare disease of red blood cells)
Viral hepatitis

A small number of cases have been known to occur after a medical procedure, such as minor surgery.

Guillain-Barre syndrome may be an autoimmune disorder in which the body produces antibodies that damage the myelin sheath that surrounds peripheral nerves. The myelin sheath is a fatty substance that surrounds axons. It increases the speed at which signals travel along the nerves.” Refer: http://www.neurologychannel.com/guillain/index.shtml

I am giving you a link for MS too: http://www.neurologychannel.com/multiplesclerosis/symptoms.shtml

The fact that the numbness in arm is worse on raising goes typically against MS and more in favor of compression especially if it involves only one arm.

Normocytic normochromic anemia is usually due to diet deficiency, worms in stomach, a bleeding ulcer in stomach or any cause of less intake of iron rich food or loss of blood. Apart from diet supplementation other causes should be looked at. A stool test will be very helpful.

Basophils are increased in allergy, viral infections and bone marrow disorders.
Hope this helps. Please let me know if there is any thing else and do keep me posted.

[Frank303]

Many thanks for your reply.
Prior to seeing the blood results I did think of DM 2 (because of feet, eye and urinary involvement My colleague suggested it even though I'm not in the risk group (normal weight), he became diabetic type 2 after a bout of Pneumonia My GP said I'm not Diabetic, though he only did a urine test. I've never had any Glucose or Ketones present on any Multistix tests I've done at home, irrespective of fasting / food /carb intake. I still have to arrange a FBG test.
The phrmacist refuses to do a test on a Friday my only afternoon off.  Would a blood glucose tester available in pharmacies be suitable for self testing/DX?

Maybe the eye hotness is due to occult allergies (Basophils are high)?

According to my blood results my anemia is normocytic/normochromic, which is probably why the iron supplements I've been taking aren't having an effect on my coldness pallor etc. Perhaps the paresthesias are anaemia related. My GP isn't looking into a cause of anaemia.

MS? Hope not. The onset to some of the apparent 'neurological' symptoms the cold swirling in my feet, sudden drops, convulsions when going to sleep and the zaps (similar to taping off SSRIs feeling) here came on the week after a Hep B booster now I've looked back on my posts. The side effects list MS, my Cousin had MS.
That the numbness gets worse after raising my arm would that be contraindicative of MS? Also I had hot spots and flashers back in the spring so they really would have been exasperated by the Hepvaxpro if it was going to induce MS.

Is Chlamydia a primary pathogen that can cause Guillain Barre, same way as Reiter's?

[Dr. Kokil Mathur]

Hi

I think we need to rule out various causes for your symptoms. One is benign intracranial hypertension. Please refer:
http://www.emedicine.com/oph/topic190.htm

“Abnormal nerve sensations such as pins-and-needles, tingling, burning, prickling or similar feelings are all known as "paresthesias". They usually result from nerve damage due to pressure (such as a pinched nerve), entrapment, or diseases. Continued nerve damage can lead to numbness.
Paresthesias can affect various parts of the body. Hands, fingers, and feet are common sites but all are possibilities.
Parethesias with simple causes such as pressing on a nerve are usually reversible. Certain other nerve conditions such as peripheral neuropathy (often from diabetes), lupus complications, Guillain-Barre syndrome, or multiple sclerosis are also possible causes of parethesias. Because of the variety of possible causes, any abnormal sensation needs prompt professional medical investigation.”

I am sure, sugar too must have been tested, though the report is not there with you. Diabetes has to be ruled out. Groin nodes can enlarge in infection of leg or groin area. Please consult a neurologist and a physician. Hope this helps. Please let me know if there is any thing else.