Undiagnosed Symptoms Community
25.3k Members
Avatar universal

Hives caused by muscle soreness/damage

Although I've struggled with hives over the past 25 years, I've had two more bouts recently. In each of these cases, I pulled a muscle and severe hives originated at the site of the pull (in the last case, my hamstring) - between 18-36 hours after working out. So it's quite clear they are related to muscle damage. I read that when a muscle is damaged, an enzyme called CK or Creatine Kinase is released. I'm wondering if I could be allergic to that and I'm having a histamine reaction to the enzyme... or perhaps it's simply a reaction to the muscle damage. These hives are terrible and even with significant dosage every 4 hours, they come and go for a week every time I get them. Any ideas?
2 Responses
875426 tn?1325528416
Have you ever been tested for autoimmune diseases?  

A loved one of mine is allergic to the bacteria from his own sweat and that can make him break out.
Avatar universal
A lot of auto-immune diseases can give hives,
Maybe you should go to the GP, and get some bloods done for ANA, DNA, thyroid and a full blood count.
I have auto-immune thyroid disease, and hives are a recurrent thing in my disease.
Also have an IGE blood test which may indicate an allergy whats causing the hives.
Wishing you well
Oh by the way apple cider vinegar baths are good for hives.
Have an Answer?
Top General Health Answerers
363281 tn?1590104173
Nelson, New Zealand
1756321 tn?1547095325
Queensland, Australia
19694731 tn?1482849837
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
In this unique and fascinating report from Missouri Medicine, world-renowned expert Dr. Raymond Moody examines what really happens when we almost die.
Think a loved one may be experiencing hearing loss? Here are five warning signs to watch for.
When it comes to your health, timing is everything
We’ve got a crash course on metabolism basics.
Learn what you can do to avoid ski injury and other common winter sports injury.
Here are the pros and cons of the top fad diets and weight loss plans of the year.