My blood glucose has always been normal. The oral glucose tolerance test showed I had pre diabetes and the insulin test showed very high insulin due to insulin resistance.
When you have one autoimmune disease and have unexplained symptoms, be on the look out for other possible conditions commonly associated. I have Hashimoto's thyroiditis, autoimmune pernicious anaemia, vitiligo and alopecia areta.
Medscape - Graves Disease...
"Graves disease is associated with pernicious anemia, vitiligo, diabetes mellitus type 1, autoimmune adrenal insufficiency, systemic sclerosis, myasthenia gravis, Sjögren syndrome, rheumatoid arthritis, and systemic lupus erythematosus."
"The authors found coexisting disorders in 9.7% of patients with Graves disease and in 14.3% of those with Hashimoto thyroiditis, with rheumatoid arthritis being the most common of these (prevalence = 3.15% and 4.24% in Graves disease and Hashimoto thyroiditis, respectively). Relative risks of greater than 10 were found for pernicious anemia, systemic lupus erythematosus, Addison disease, celiac disease, and vitiligo."
Have you ever been checked for Fibromyalgia? It's very painful and comes with a lot of the symptoms you described
I was tested for pernicious anemia and RA. Celiac panel negative. Cortisol was on the high side of the range, specialist said it's not enough to be anything adrenal.
ANA was done 2012 when I was diagnosed with Graves (I don't understand it):
Anti-CCP IgG Ab - less than 1 (range less than 5)
ANA - Borderline
ANA Titre 1 - 1:40
ANA Pattern 1 - Speckled
dsDNA - Negative
ENA Screen (11 antigens) - Negative
I will see a new doc and get the oral GTT.
Is there a specific test for Fibro? The specialist mentioned it along with CFS once, but said they were pretty much a diagnosis for when everything else suspected is ruled out.
Hi S_9, have you ever been tested for vitamin D deficiency? All your symptoms sound exactly like what I just read on the Vit D forum.
I was just diagnosed with vitamin D deficiency myself (normal range is 30-100 with 50-80 optimum; my level was 19). I share a lot of the same symptoms that are plaguing you. At first I thought, well doesn't everyone have a vitamin D deficiency? How could THAT be the problem? But the more I've read, the more I'm persuaded that this is the cause of my symptoms (extreme fatigue, poor concentration, rapid/irregular heartbeat for no reason, muscle and bone pain, weakness, headaches, etc.)
You have some additional symptoms that I don't share, but I read of others with vitamin D deficiency also reporting them: increased thirst, skin problems, trouble sleeping.
I hope you are able to check it out, and that this information helps you.
I have been tested, I take D3 (I think) sometimes just to up it a little because it has been low range. The results I have say 85 (range 74-174), and previously 63 and 64 (range more than 50, optimum more than 75). When I ask for this oral GTT I will see if the doc will get me another vitD to be sure.
Thanks for letting me know :)
Still open for ideas if anyone else happens to read this, too.
There are no diagnostic tests yet available to definitively identify fibromyalgia.
This info is from Family Practice Notebook - ANA Staining Pattern...
"III. Speckled Pattern
Most common, least specific
Systemic Lupus Erythematosus
Mixed Connective Tissue Disease
Smith Antibody (Anti-Smith)
Ribonucleoprotein Antibody (Anti-RNP)
Scl-70 kD kinetochore (Anti-Topoisomerase I)
Optimal calcium absorption occurs with a vitamin D level greater than 79.8 nmol/L (32 ng/mL). Optimal disease prevention (vitamin D deficiency is highly linked to numerous diseases including cancer) at a minimum of 125 nmol/L (50 ng/mL).