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What is the actual difference between Wellbutrin XL and Wellbutrin SR.  Will both cause the same weight loss.
11 Responses
106886 tn?1281291572
Hi Dixie,

Boy, I think that the difference is simply how they are released into the system. Typically Wellbutrin was initially introduced as a pill you take 2 times a day (maybe that was depending on the dose, but I am pretty sure this is the case)...so if someone was on 100 mg of Welbutrin the dose would be 50mg in the morning and 50 mg around 4 pm. Then they came out with a sustained release tablet only to be taken once a day...yes...that is it!!! Sustained Release. Now if someone challenges that info, I will certainly be open to it, but I am pretty sure this is what it means. You could always phone a pharmacist to be sure. They are very knowledgeable.

Not sure of  your exact question regarding weight loss. I do know that sometimes Wellbutrin helps in cases where people have cravings and/or addictions (to gambling for example and also nicotine I think)...and I also know that people do not experience the same problems regarding weight loss as they do with the other SSRI anti-depressants such as Zoloft and the like.

Take care,

Avatar universal
Wellbutrin XL is once a day and the Wellbutrin SR is twice a day.  I was recently on the XL and I didn't loose any weight, I actually gained some. But thats just me, I have heard it works wonders for some people.
Avatar universal
I was so excited about taking Wellbutrin SR for my anxiety and weight loss it worked for my depression but, not for the weight loss.  I take one tablet 150mg daily in the am.  Please help!!!!!!!!!
Avatar universal
If your taking something else(which may cause weight gain) that very well could be what's blocking Wellbutrin from making you lose weight.
Avatar universal
My Mom just went back on Wellbutrin SR, and she was on Paxil for years before. Since being on the Wellbutrin for 2 weeks, she already lost 7 pounds. I heard this is the skinny, happy pill.
Avatar universal
I have been taking wellbutrin for 8 years.  I was originally considering weight loss surgery and had many reservations about it.  I had to go to counseling before my health plan would do the weight loss surgry and the social worker saw my hesitancy and suggested wellbutrin for weight loss.  My mother had taken it for depression when it first came out and lost 60 pounds and kept it off. I always wondered how she kept her weight off and then now I know it must have been the wellbutrin.   I went from 325 to  225 in 2 years.  While it is not as effective as originally for weight loss, I have kept the weight off that I lost and never fluctuated more than 5 pounds.
For me it has been a miracle drug, and while I had initial side effects of constant dry mouth and a tremor they have disappered.  When I take more than 200 mg. a day I sometimes have trouble urinating.  While I wonder about the long range side effects, I am afraid of going off it all together as I don't want to gain my weight back.  I still need to loose more weight, and keep hoping the medical community will find another relatively safe drug for people like me to control appetite.  
Avatar universal
I have been on Wellbutrin for nine years, I am beginning to wonder if at some point it "stops working" I am on the maxium dose. I have tried ever other antidepressent known to man/women kind! It seems to be one of the few ones that works! Or perhaps just more life stressors. Anyone else have this problem?
Avatar universal
I too have been on Wellbutrin for a number of years. It definitely does not have the same positive effects on my depression as it did in the beginning. One thing I am curious about is if the generic form doesnt work as well. I switched to the generic brand a few years back. anyone have any thoughts on that?
2035835 tn?1336300786
Hi I have a question about  when you stared taken the wellbutrin was it the sr or the other kinds? And did you get the generic? And did you start loseing the weight right away? sorry for all the questions... I'm just really trying to lose some weight so my doc put me on wellbutrin.
My doctor prescribed Wellbutrin SR 150 mg a couple of days ago for weight loss since exercise and diet don't work to lose the 20-30 lbs I gained on other medications. He said it would boost my metabolism. I'm excited but noticed a touch of insomnia last night (woke up a couple of times and woke up earlier in the morning than usual). I've just read that once you stop taking it, you can gain the weight back. I was hoping to only take Wellbutrin for 6-9 months than stop taking it. Is the boost in metabolism truly only temporary? Will one gain weight after stopping to take Wellbutrin?
Avatar universal
Thank you that was quite helpful. Which Wellbutrin you were referring? Is it Wellbutrin SR that help you with weight loss?
Avatar universal
Those are usually given for seizures and maybe for depression or severe anxiety but they're definitely not the appetite suppressants and they're not didrex or Phentermine and the anti-seizure seizure medication drug you're speaking of I don't recommend I know people who have taken them for a year and they have many bad problems from taking them because they took them for over a year don't use the seizure medicines to try to lose weight they're not for weight reduction go to a doctor or nurse practitioner specializing in weight reduction
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