My situation is very similar to yours. I was on the drug for approx 1 year in the beginning I didn't notice much weight change, but I worked out regularly and was always conscious of what I was putting in my mouth then in the last 4 months on it I gained about 20 lbs. I've been off it for about 3 weeks (completely off...it took about 6 weeks to ween myself off) and I have continued to gain. I also think the effexor may have caused issues with my thyroid. Please let me know if you have learned more.
I experienced the exact same symptoms as yours. I was on 300mg for 5 yrs and when it came to weaning myself off, I went down to 150mg and then stopped when I ran out. I suffered through the withdrawals which were absolutely horrible. When I started taking it, I only weighed 123lbs, now I weigh 212lbs. I've only been off it for a week, my withdrawals are completely gone and I have a ton of energy now. I feel like I can't stop talking, I always seem to want to dance my *** off when I hear music playing which is something I never had the energy to do before. I feel really great right now! I used Effexor in prior years but only for a year. I gained a ton of weight then too. At my highest, I weighed 187lbs. After coming off them that time, it took 3 months to get down to 123lbs. It fell off like nobody's business and I was eating all the time.
Hi All,
I'm in very poor health due to an extremely painful genetic condition. I had taken effexor for years, Rx'd off-label for pain. I was never certain if it helped but all of my drs insisted it was and without it the pain would have been far worse. Around 2007 I had insurance & financial issues and simply couldn't afford to pay for all my meds. Effexor had to go. Yes. Severe vertigo and feeling horrible. But I did it. I did indeed lose weight but never put it together with cutting out the effexor. Still wasn't certain that it was a benefit at all to my pain but I will tell you one thing I did discover: While taking effexor I experienced amazing earth shattering orgasms and that was completely gone the effexor completely cleared my system. I hadn't put the connection together prior as I had assumed my better experience was due to a better partner. Sadly, not so much. I confided this to my endocrinologist who told me most experience sexual dysfunction on antidepressants but a small percentage of women will experience extra-orgasmic effects. She had me go back on 37.5 mg and yes, my amazing sex life returned! When I read people asking, "Why would anyone ever wish to take this poison?" I can tell you, I definitely know one reason why! As time passed my pain management team again wanted me to increase the dose, in distant that it would help block the pain message getting to my brain. Still never certain that's ever worked. Now it's years later, I've been single 2 years with no prospects on the horizon. I've gained 50lbs whilst on the effexor over the last, what, 6+ years. I never put it together with effexor. I have a horribly poor appetite as pain keeps me eating and can also lead to vomitting. For years I kept track of every calorie and would report to my drs something was amiss. I never ate more than 1250 calories a day, an average day for me has been 750 calories. They either haven't believed me or have been mystified. One 10 day hospitalization the facts were in their face. I entered hospital and was weighed on the hospital scale, 199lbs. After a week in bed I told my nurse I felt heavy, she brought in a scale, I kid you not, I was 247lbs. Most important factor I neglected to mention, dr increased the effexor to 225mg during my stay. One dr in particular couldn't believe it. Refused to believe it. He demanded a pair of orderlies drag up the massive scale used in admittance. True enough, on the same scale I had weighed 199lbs about a week earlier I now weighed 242lbs. First, he started to argue that I hadn't gained the 48lbs they had first thought but 43lbs! I calmly asked if that really mattered? The point was that they knew exactly what I had been eating and my weight had gone up 20% in a period of less than 10 days. Ridiculous. After release I struggled and have been able to get my weight down to 220, then I plateau. Dr tried to insist it was all water but still, I asked how could that be? I was not hooked to IF and there was no way I was drinking 40lbs+ of water! I took the diuretics he Rx'd but still only got down to 220 in the year since that happened.
So now a different dr wanted me to start a different med for my condition but it was contraindicated with effexor. Again, I told him that I never really knew if the effexor helped with the pain as the pain has only continued to worsen. Convinced him it was time to dump the effexor once and for all and try the new med he thought may benefit my genetic illness. I'm single and not getting any anyway, right? I'm at day 5 of weaning down, down to 37.5 mg. Yes, I've had some vertigo and nausea. And yes, maybe it has been helping with the pain because the pain level has definitely jumped a few notches. But sheesh, I've already lost 6lbs. Wtf? Swear to you, after all these years, today was the first day I googled, weight loss with effexor withdrawal and weight gain with effexor. I have to take so many medications I just assumed by telling my drs that I barely eat and have put on 50-60lbs over the last 6 years (90 if you count how high I went in hospital when they upped my dose) that one of them would figure out why or tell me that one of my meds was known for such weight gain. Nope. Not one.
Soon I will be completely off effexor. Fingers crossed I will lose the 50lbs or near to it! If there is another man in my life at some point, well, either I'll make him work harder or I'll investigate if there are other antidepressants out there that can offer me the same orgasmic bliss.
Good luck to us all!
Get off the Effexor A.S.A.P!!! I was on it for anxiety, and it made me go from super anxiety and emotional to numb! I hated it. I would rather feel something then nothing. Now...I was on 325mg for 4 months. I gained 30 pounds in that short period of time. I have been off the meds for 4 and a half months, exercise 4 to 5 times a week and on a 1200 calorie diet and can NOT seem to lose even 1 pound. Effexor was the worst mistake I even made.
Get off the Effexor A.S.A.P!!! I was on it for anxiety, and it made me go from super anxiety and emotional to numb! I hated it. I would rather feel something then nothing. Now...I was on 325mg for 4 months. I gained 30 pounds in that short period of time. I have been off the meds for 4 and a half months, exercise 4 to 5 times a week and on a 1200 calorie diet and can NOT seem to lose even 1 pound. Effexor was the worst mistake I even made.
I am so happy I found this thread. I started effexor in April 2014 and it is now almost September and I have gained 25lbs. I know everyone is different and has different side effects but this medicine is the culprit for me. I have had gastric sleeve surgery and never had the appetite I have now that I am taking this medicine. And as someone else pointed out, I rather be thin and a little miserable than fat and happy. I am not even happy at this point because one of my biggest depression triggers is when I was extremely overweight before my surgery so now that I have gained weight, all those awful feelings are coming back. I am only on 37.5mg and I am going to start weaning myself off immediately. I hope I dont' have the awful side effects everyone is talking about. I am a single parent with 2 kids and I need to be functioning 100% of the time. I also take Prozac but have been taking if for years and have never had this problem like I've had with the Effexor. I wish all of you the best of luck, hopefully we can move on and try something different or natural. These medicines cannot be good for our bodies.