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Methotrexate, ectopic pregnancy and bleeding

I have had two doses of Methotrexate administered by a needle. Between doses, the embryo grew from 2.8 cm to 5.8 cm in a span of a week. My Bhcg went from 2600 down to a little over 900. Was at the hospital under observation but have been released. This is my first night home, and I am concerned about what can happen. Experienced a fainting spell while under observation, low blood pressure after, but since then went up. Still ight headed, bleeding light to moderate, bright red, no tissue or clots. Slight cramping in my left side (where ectopic was discovered). Does anyone have any similar experiences or experienced this? What was the outcome? Am I just paranoid, or am I in grave danger at this point? ALL honesty is respected, will not get offended. Thank you
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Avatar universal
I am sorry to hear about everyones experiences but it is also nice t know that there are some people like me out there. On 9/1, I started what I thought was my period. Everything seemed normal...breast tenderness, cramps, menstrual bleeding. After a week, the bleeding seemed to be stopping, and then came back more heavily. I wasn't alarmed because I have PCOS and adenomyosis and the adenomyosis sometimes causes me to have long periods. After bleeding for 3 weeks, light to heavy flows with huge clots I started getting really fatigued, which never happens. I thought maybe I was having a misscarriage because of all the clots and called my doc. They did a urine pregnancy test and I was shocked that I was pregnant since I was on birth control and Metformin (for my PCOS). They did a pelvic ultrasound and saw nothing, and I was in pain from the ultrasonographer pushing down on me and moving the tube around. They also test my blood and I was at 1000, which she said was good. That night I went home and cried for hours. I didn't expect that it would effect me, but I lost it. It's a lot of physical and emotional pain. The next day, I got a shot of Methotrexate ( 1 in each cheek) and have to come back next week for a blood test. I had pretty bad cramps the night after, but the doctor told me that was normal. I just pray that the Methotrexate works and my levels will drop. In about 6 months, we're going to try for a successful pregnancy.

Thank you all for sharing your stories, I have learned something from everyone and am glad that I am not alone.
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1807749 tn?1316471459
Hi Im new also, I also am/was in the same boat. I do have a 21 yr old son. And I am 39 yrs old now. I did to have an ectopic back in Feb. 98 was removed at 6 wks cause of hemmorraging didnt know it was ectopic at that time.
In 8/08 I decided to have an ablasion done, didnt plan on having anymore children. Well its 2011 and I have moved to a different state cause got divorced, and with a new man, he has 2 beautiful children 5 & 7.
Well to make long story short, went to a routine obgyn appt cause I was spotting and having discomfort, thought it was just a cyst. Doc took urine and said, as I was getting dressed take ur clothes back off ur pregnant....I almost passed out and said dont joke about things like that, well I was pregnant so we did an ultra sound it was twins in my left tube and I was 4 to 6 wks. She sent me to the hospital, had my hcg level taken, then the methotrexate shot. Had my blood ran a week later and it was at 4300. I had 1 bad nite of horrible pain used a heating pad and took tylenol that next morning I did pass them they were attached and looked like 2 small cloudy lima beans. I am still having pain on my left side but its not horrible. I was told that is because your tube does get irritated and sore cause of the swelling due to pregnancy thats not suppose to be there. If I have a bowel movement or bladder gets full it does cause pain for my tube.

I have read everyones comments and I am sorry for ur loses. I am glad there is a place that you dont feel alone and someone else has experienced similar problems. Thanks again.
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Avatar universal
I know all too well about this nightmare. Last Sept I ended up with my first pregnancy ending up being ectopic. I had pain on and off for two days, I knew I was pregnant, about 6 weeks, as my husband and I had been trying. I waiting way to long to gonto the ER, and by the time I got there it had ruptured, and they rushed me into surgery where they removed my right tube. I lost so much blood from bleeding internally that I needed a blood transfusion.
Exactly a year later to the day, I found out that we were finally pregnant again. We had been seeing a fertility specialist, had 2 unsuccessful IUI's, and got pregnant naturally the month before out first IVF. I was over the moon, and so grateful God had blessed me with this miracle the month before IVF. I was being monitored very closely because of my history, end everything was going perfect, for about a week and a half. Then at about the same time in my last pregnancy I got that familiar pain in my tube that I will never forget. The pain was so bad, that I vomitted from it! I went straight to the ER in fear of losing my only tube if it ruptured. The first ER misdiagnosed me after I told them it was ectopic and sent me home claiming my tube was clear, and there was an empty gestational sack in the uterus, and it was probably just too early to see a yolk sack or fetal pole. At that time my HCG levels had leveled off, so I knew something was wrong. That same night, the pain came on again, and I drove myself to the ER closest to my house, the one that had did my surgery last year. After the US the OB on call came in and said there was a 2 mm mass in my right tube and he wanted to remove my other tube and leave me without any tubes at 33 years old without any children. I have wanted to be a mommybsinve I was a little girl.
I begged the DR to try and save the tube, but he warned me that it doesn't function properly if this was my second ectopic and it would only put me risk for another ectopic. But we went to surgery and he attempted to save it anyway for my peace of mind. BIG MISTAKE! Turns out he left too much tissue in the tube and a week after surgery my HCG had leveled off again and wasn't decreasing. I was starting to feel pressure in the tube again. Apparently it an grow back if he doesn't get it all, lovely! So the wanted to give me methotrexate and I was completely against it. I begged 2 dr's to just get me back in the OR and take the tube. Neither of them would, and they gave me no choice. So yesterday I had my first shot, and I begged the nurse for pain meds, as I have read how painful it is from the girls that have been through it. The told me no, that it would mask the pain, and I needed to come in if I was in pain. Last night and this morning was the worst cramps I have EVER had, and I knew that I could not continue without meds, passing the grosses clots that looked like my uterus fell out. I went back to dr for blood work, and unltrasound, and he told me this was normal and I wasn't bleeding internally, which I knew, and finally gave me some pain meds. Having 2 ectopics, I knew the pain was different, but I should not have to suffer like this when I am already in pain and trying to heal from my surgery last week.
I keep wondering when this nightmare will ever end. I am so angry that now I have to wait another 3 months before I can do our first IVF because of this stupid shot they forced me to have. Having been through surgery, I would prefer that pain anyway, rather than the pain from that awful shot. Listen to your body, that's my advise. I knew something was wrong, even though the hospital told me my tube was clear. It is terrible how you have to be your own dr these days!!! Just terrible. I have joined an amazing on line support group called Daily Strength, I highly recommend it to anyone suffering with infertility and miscarriages. Be well, be blessed, Carla
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Avatar universal
So sorry you're having to go through this... hang in there! I know it's a tough time but it WILL get better!  My testing lasted a couple weeks then I had methotrexate, more tests, and ended up needing surgery after all.  I remember those points of anxiety and frustration.  It's a day-by-day thing, but know that others have been there.  Don't be afraid to share your feelings with a close friend or spouse; I found this to help.  The surgery and recovery was quick proved to be the best choice for my body.  If it helps to know... I'm feeling MUCH better now and will be praying for you!!  Let me know if you have questions.
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Avatar universal
I am a week out from one dose of methotrexate following diagnosis of an ectopic pregnancy.  I am 32 years old, had never had an IV in my arm and the thought of surgery was overwhelming.   I am now wishing more than anything that I'd had the surgery.  This process and the hormonal roller coaster through hell that it has been is just too much.  I would do anything to have it all over with and just be recovering, which is where I'd be if I'd had the surgery.  Instead, my bhcg doubled in 4 days, didn't come down the 15% my doc wanted so am now getting it monitored every other day, my breasts are still tender and sore, and i have absolutely no signs of bleeding, meaning that my body is still very much in pregnancy mode.  I would not wish this upon anyone.  all I want is for it to be over with and behind me, and it looks more and more like i'm still weeks away from that.  I know it is a process, but I had no idea just how long and emotionally exhausting it would be.
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Avatar universal
Hello everyone,
Really sorry to hear about the losses of everyone and hoping that everything gets better for everyone here,
Just wanted to share me story and experience.
I got a positive pregnancy test on 21st June and started spotting on 25th June. Went to the doc, they did ultrasound but couldn't see anything in the uterus, they thought it might be too early. The next day I get severe gastrointestinal problems and I am doubling over with pain. Went to the hospital, they did ultrasound and found fluid in my abdomen. On 29th June, I had laparoscopic surgery to remove the blood from my abdomen but the doc said that the pregnancy was not in the tubes, it was in the abdomen probably which is a very rare case. Doc still couldn't identify exactly where the pregnancy was, but since he removed all the blood and clots from abdomen, he said that hopefully all pregnancy tissue has been removed.
Anyway, I get some blood work done a week later and my HCG had increased to 4500 (it was 1100 when I had the surgery). Doc said that there was probably some tissue left, so he started me with oral methotrexate for a week. Thankfully, after a week, my levels had dropped to 4000; not very fast but still it was dropping. The doc has continued my oral methotrexate for another week and I have to get more blood work done today and then on Friday.
However, I have had severe side effects with methotrexate. Severe Abdominal cramps, constipation, trapped gas, and bloating. I have a bit of spotting and bleeding but I won't probably pass a clot or sac since my pregnancy was in the abdomen and not in the uterus or tubes. I rushed to the ER twice because of pain in the fear that I had started to bleed internally like before but the ultrasounds showed everything to be normal, so I know it's just the side effects of metho.
Just hoping and praying that my levels drop drastically in the blood works now. Do pray for me as well girls :)
You will all be in my prayers!
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