Hey Harry... I have tried quite a few of the meds for breakthrough pain including lyrica and like Quix says you have quite a bit of room to increase that dosage. I gave up on lyrica myself and I have been constantly on Carbamazepine 300mg tid for a long time and now I am using 40mg of Amitriptyline at bedtime. The breakthrough pain is not too bad now and I am only having trouble with pain from a different source at the moment that I am going to have to discuss with the dr. I wish you luck with your pain control my dear and I know it can be darn frustrating. I have been on Carbemazepine for about 15 years and have tried Topamax, Gabapentin, Lyrica all in combination but the Amitriptyline (Elavil) seems to have done the trick. Apparently it is a drug that used to be used as an antidepressant and now they use it almost strictly for pain control and it apparently works by making your R.E.M. sleep more restful or something like that...all I know is that it works for me and the only side effect is a dry mouth.
Lots of Hugs,
Rena
Hi! We had a little discussion on treating neuropathic pain yesterday on the Discussion called, "Update: Neuropathy" by treebranches.
You have room to increase the Lyrica dose, I believe, by quite a bit. Also there are other meds which can be added in to increase the effectiveness of the Lyrica. You might talk to your doctor about adding a low dose of amiltriptyline at night or possibly adding carbamazepine. I know that carbamazepine can be used with gabapentin (Neurontin), so it "should be okay with Lyrica.
Carbamezepine is FDA-approved in the US for use in Trigeminal Neuralgia, which is one of the most severe nerve-pain syndromes known. It is also approved for use in diabetic neuropathy which can be severe and is often of a burning nature.
Take a look at that discussion. It is still on the first page.
I am going to try to write up something a little more comprehensive on treating nerve pain. I know very little about it and the issue comes up a lot.
I'm sorry to hear of the suspicion that you have PPMS. It is harder to diagnose and takes longer to get enough evidence together to make the call.
Quix