What is amoxicillin, clarithromycin, and lansoprazole?
Amoxicillin is an antibiotic in the penicillin group of drugs. It fights bacteria in your body.
Clarithromycin is in a group of drugs called macrolide antibiotics. Clarithromycin fights bacteria
in your body.
Lansoprazole decreases the amount of acid produced in the stomach.
The combination of amoxicillin, clarithromycin, and lansoprazole is used to prevent stomach
ulcer caused by infection with Helicobacter pylori (H. pylori).
Amoxicillin, clarithromycin, and lansoprazole may also be used for other purposes not listed in
this medication guide.
What should I discuss with my healthcare provider before taking amoxicillin, clarithromycin, and lansoprazole?
You should not take this medication if you are allergic to amoxicillin (Amoxil, Trimox,
Dispermox), clarithromycin (Biaxin), lansoprazole (Prevacid), or to any of the following antibiotics:
-
ampicillin (Omnipen, Principen);
-
azithromycin (Zithromax);
-
carbenicillin (Geocillin);
-
dicloxacillin (Dycill, Dynapen);
-
erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin);
-
oxacillin (Bactocill);
-
penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K,
Pfizerpen, V-Cillin K, Veetids, and others);
-
telithromycin (Ketek); or
-
troleandomycin (Tao).
Taking any of the following medicines together with
amoxicillin, clarithromycin, and lansoprazole can cause a life-threatening side effect on your
heart:
-
cisapride (Propulsid);
-
ergotamine (Ergomar, Cafergot, Ercaf, Migergot);
-
dihydroergotamine (D.H.E. 45, Migranal Nasal Spray),
ergonovine (Ergotrate); or
-
pimozide (Orap).
If you have certain conditions, you may need a dose adjustment or special
tests to safely use this medication. Before taking amoxicillin, clarithromycin, and lansoprazole, tell your
doctor if you have:
FDA pregnancy category C. Clarithromycin may be harmful to an
unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become
pregnant during treatment.
Amoxicillin can make birth control pills less effective, which may result in pregnancy. Before
taking amoxicillin, clarithromycin, and lansoprazole, tell your doctor if you use birth control pills.
Amoxicillin, clarithromycin, and lansoprazole can pass into breast milk and may harm a
nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take amoxicillin, clarithromycin, and lansoprazole?
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or
for longer than recommended. Follow the directions on your prescription label.
Each dose of this combination medication contains 4 pills ( 3 capsules and 1 tablet). Take all 4
pills twice daily before you eat, unless your doctor tells you otherwise.
Do not crush, chew, break, or open the pills. Swallow each pill whole. You may swallow
the pills one at a time.
Take this medication for the full prescribed length of time. Your symptoms may improve
before the infection is completely cleared. Amoxicillin, clarithromycin, and lansoprazole will not treat a
viral infection such as the common cold or flu.
This medication can cause you to have unusual results with certain medical tests. Tell any
doctor who treats you that you are using amoxicillin, clarithromycin, and lansoprazole.
Store this medication at room temperature, away from moisture, heat, and light.
What happens if I miss a dose of amoxicillin, clarithromycin, and lansoprazole?
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait
until then to take the medicine and skip the missed dose.
Do not
take extra medicine
to make up the missed dose.
Where can I get more information about amoxicillin, clarithromycin, and lansoprazole?
Your pharmacist has information about amoxicillin, clarithromycin, and lansoprazole written for health professionals that you may read.
What are the possible side effects of amoxicillin, clarithromycin, and lansoprazole?
Get emergency medical help if you have any of these
signs of an allergic
reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
-
diarrhea that is watery or bloody;
-
signs of new infection, such as fever, chills, body aches, flu
symptoms, mouth sores;
-
easy bruising or bleeding, unusual weakness;
-
agitation, confusion, unusual thoughts or behavior;
-
dizziness, fainting, fast or pounding heartbeat; or
-
fever, sore throat, and headache with a severe blistering,
peeling, and red skin rash.
Less serious side effects may include:
-
unusual or unpleasant taste in your mouth;
-
headache;
-
nausea, vomiting, stomach pain;
-
constipation, dark colored stools;
-
dry mouth, increased thirst; or
-
vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your
doctor for medical advice about side effects. You may report side effects to FDA at
1-800-FDA-1088.
What is the most important information I should know about amoxicillin, clarithromycin, and lansoprazole?
You should not take this medication if you are allergic to amoxicillin (Amoxil, Trimox,
Dispermox), clarithromycin (Biaxin), lansoprazole (Prevacid), or to certain other antibiotics.
While you are taking amoxicillin, clarithromycin, and lansoprazole, do not take any of the
following medications: cisapride (Propulsid), ergotamine (Ergomar, Cafergot, Ercaf, Migergot),
dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or pimozide (Orap).
Tell your doctor if you have kidney or liver disease, myasthenia gravis, or if you are allergic to
any drugs (especially any antibiotics).
Amoxicillin can make birth control pills less effective, which may result in pregnancy. Before
taking amoxicillin, clarithromycin, and lansoprazole, tell your doctor if you use birth control pills.
There are many other medicines that can interact with amoxicillin, clarithromycin, and
lansoprazole. Tell your doctor about all your prescription and over-the-counter medications, vitamins,
minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication
without telling your doctor.
What should I avoid while taking amoxicillin, clarithromycin, and lansoprazole?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have
diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the
diarrhea unless your doctor has told you to.
What other drugs will affect amoxicillin, clarithromycin, and lansoprazole?
Many drugs can interact with amoxicillin, clarithromycin, and lansoprazole. Below is just a
partial list. Tell your doctor if you are using:
-
HIV/AIDS medications such as atazanavir (Reyataz), ritonavir
(Norvir), or zidovudine (Retrovir);
-
a blood thinner such as warfarin (Coumadin);
-
clopidogrel (Plavix);
-
cyclosporine (Gengraf, Neoral, Sandimmune);
-
digoxin (Lanoxin, Lanoxicaps);
-
iron supplements (Feosol, Fergon, Slow Fe, and others);
-
fluconazole (Diflucan) or ketoconazole (Nizoral);
-
probenecid (Benemid);
-
rifabutin (Mycobutin);
-
sildenafil (Viagra);
-
tacrolimus (Prograf);
-
theophylline (Elixophyllin, Theo-24, Uniphyl, and others);
-
a sulfa drug (such as Bactrim or Septra);
-
HIV/AIDS medications such as atazanavir (Reyataz),
ritonavir (Norvir), or zidovudine (Retrovir);
-
cholesterol-lowering medicines such as atorvastatin
(Lipitor), simvastatin (Zocor), lovastatin (Mevacor), and others;
-
a heart rhythm medication such as disopyramide (Norpace)
or quinidine (Quinaglute, Quinidex, Quin-Release);
-
a sedative such as alprazolam (Xanax), midazolam
(Versed), or triazolam (Halcion);
-
seizure medication such as carbamazepine (Equetro,
Carbatrol, Tegretol), phenytoin (Dilantin), or valproate (Depakote, Depakene); or
-
a tetracycline antibiotic such as demeclocycline
(Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin,
Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).
This list is not complete and there may be other drugs that can interact with
amoxicillin, clarithromycin, and lansoprazole. Tell your doctor about all your prescription and
over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other
doctors. Do not start a new medication without telling your doctor.
What happens if I have an overdose of amoxicillin, clarithromycin, and lansoprazole?
