Members,
There's been some interest and debate here on the effects on PEP on seroconversion in patients who seroconvert, so I did some research. Here's what I've found:
The general consensus is that PEP does not, except in rare circumstances, impact the time to seroconversion.
Links/Excerpts:
http://www.dhs.ca.gov/aids/Resources/pdf/pepguidelinesfinal.pdf
A case of delayed seroconversion in a treated monkey suggests that delayed seroconversion may occur in the context of human PEP, although this has not been reported in either the occupational or non-occupational setting except during co-transmission with hepatitis C [4, 11, 29].
http://www.thebody.com/cdc/pep/pep06.html
Three instances of delayed HIV seroconversion occurring in HCWs have been reported; in these instances, the HCWs tested negative for HIV antibodies >6 months postexposure but were seropositive within 12 months after the exposure. Two of the delayed seroconversions were associated with simultaneous exposure to hepatitis C virus (HCV).
Related:
http://italia.medscape.com/viewarticle/513928
There are currently 6 worldwide case reports of HIV seroconversion despite combination HIV PEP. (2003 study)
http://www.hivinsite.org/InSite?page=pr-rr-07-01-05
[Effectiveness of nPEP]