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Dangers of long-term Phenergan usage?

Hi, I have severe allergies and the resulting nasal congestion and asthma makes it very hard for me to sleep at night. I have tried dozens of sedatives and sleeping drugs (as well as the whole meditation, therapy angle) and surprisingly, the most effective solution has been 20 - 25mg of phenergan each night. My immunologist expressed concern about me taking phenergan every night, but I have been doing so for about 3 months now will no ill effects.
Does anyone know if there is a danger of taking this strong dose of Phenergan regularly for a long period of time?
Thanks!
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Avatar universal
I would not recommend taking this. I had really bad Nausea in high school so I was prescribed this and after a few months the nausea went away but then I started having Essential Tremors and it has been five years since I've had Promethazine.
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Avatar universal
they gave me one shot of the stuff in the hospital and the twitching happened immediately for me, it took me months before the twitching stopped completely. I would have bouts of twitching/must move or go crazy. I don't advise anyone to take this stuff, its scary when you don't have control over your own body.
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Avatar universal
I have been taking 100mg a day of phenergan for 3+ years for chronic nausea.  I don't know what I'd do without it.  I'd be vomiting all day long.
My question is - does the effectiveness of phenergan wear off after long term use.  Also Zofran or meclizine doesn't even touch the nausea.
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Avatar universal
I was given Phenergan 50m to take at night because I had the shingles on my head and now have really bad itching and this keeps me awake.
it makes me drowsy but I get crazy restless legs. I have to keep getting up and walking around the house. also have to drink a lot of water for the dry mouth that comes with it too.
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Avatar universal
I took promethazine on and off for three years and now suffer form long term effects years later. I have restless leg and jerk at night as I fall asleep (Parkison type symptom). This symptoms is a noted side effect of long term use and had I been cognizant of this information I would have never used this in the first place. I now take meclazine for my balance and stomach issues. The balance issues is another long term side effect form the promethazine. At the time it felt like a miracle drug, but in the aftermath it is a demon. These side effects have not subsided nor do I believe they will go away ever. Personal- not professional recommendation: Stay far away from this stuff!
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8944740 tn?1400753841
I need to know as well.  Starting reduction tonight after 2. months on 25mg.

I have read all of the comments following this post and, for those who are suffering from restless legs (phenergan related or not) MAGNESIUM is fantastic for this.

Also, I have found that propananol 40mg helps greatly with palpitations and tremors.  At least it does for me if I take a lower dose of Phenergan.  BE AWARE - propananol is a blood pressure medication so see your Dr.

Good luck to all.
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