My boyfriend went to his dad's house yesterday and all of the sudden he breaks out in HIVES! Or, at least they look like hives. When he was younger, he had his spleen removed and was required to take penicillin every day since his immune system is weak without his spleen (which he stopped taking it every day a few years ago :/... ) I have never seen this boy break out in hives and all of a sudden--BOOM! Here they are. He says that his palms are the worst. He says they itch very badly, and it is painful to grab stuff. He took pictures of the rash the night before and it looks like millions of mosquito bites in some areas. But the strange part is that it is moving DOWN his body. Yesterday, it was all over his body, but the worst on his palms, arms, chest, and abdomen. Today, he still has small whelps in spots on his arms and chest, but it has NOW moved down to his hips, thighs, knees, and tops of his feet. BUT his palms still are itchy and tender. He says he has NO fever, but his joints are aching...? He says he has NOT been in the woods, so we could possibly rule out tick bites. He doesn't eat anything out of the ordinary, just plane-jane food (pizza, burgers, guy food), so no food allergies so far. Please give me some suggestions. I'm worried about him.