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Indomethacin: other methods of taking it

A year ago I was diagnoised with Hemicrania Continua. It’s a headache disorder that responds really well to Indomethacin (in fact for the most part it only responds to Indomethacin). In my case it only responds to Indomethacin. It took a year to dx me and in that time I tried many different treatments.

Some people are able to cut back on their dose of Indomethacin or stop it completely w/ no more headaches, I am unable to cut back or stop.

I have trouble tolerating Indomethacin and all NSAIDs. To try and overcome this I take Omeprazole and Ranitidine as well take the Indomethacin with a meal. Taking so many pills at such a young age is a bit fusterating and can be very controlling of my day to day life. It’s frustrating to have to eat 3 large meals a day rather than split it up into smaller ones.

So I have started thinking about other ways to receive this drug, suppositories are out of the question though.

So I was wondering can Indomethacin be delivered via injection? Then it would bypass my stomach and I could stop taking the stomach meds. Also, wouldn’t I be able to take a smaller dose then because the way it was being delivered?

or

Could it be delivered via a pump, similar to the insulin pumps? Wouldn’t that also allow for a smaller dose to be used as well as avoiding most side effects?

Are any of those options? If not, are there any options?

Thanks!
3 Responses
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616411 tn?1221764253
MEDICAL PROFESSIONAL
For that I would have to direct you to your prescriber. Or call the manufacturer at the number I listed above in the previous response. Unfortunately those seem to be the best solutions I can recommend at this time. Sorry I don't have a better answer for you. .

Jennifer R RPh www.drugstore.com
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Avatar universal
So there isn't anyway to do the iv infusion at home? Does it have to be in a hospital setting?

I cannot do the suppositories... end of story.

I have tried all the other options you have listed, none have worked.

It took a year for me to be dx with this and get the correct treatment, during that time I tried many different treatments none which worked in the least bit.
Helpful - 0
616411 tn?1221764253
MEDICAL PROFESSIONAL
Here is the manufacturer information for the company that makes injectable indomethacin. However keep in mindit is not a possible daily option in that this is via IV infusion and is administered by a trained health care professional over 20-35 minutes in hospital setting.
Ovation Pharmaceuticals, Inc
Four Parkway North, Suite 200
Deerfield , IL 60015
800-455-1141

I would probably suggest you reconsider using the rectal suppositories. If you know this medication works for you , rectal administration is a very effective way for your body to get the medication that you require for your headaches.

With regards to pumps, etc I am not aware of any delivery systems, however I would discuss that option with your prescriber.

Indomethacin, a non-steroidal anti-inflammatory drug (NSAID), usually provides rapid relief from symptoms. Other NSAIDs, including ibuprofen, celecoxib, and naproxen, can provide some relief from symptoms. Amitriptyline and other tricyclic antidepressants are effective in some patients. Explain to your doctor/prescriber how you feel about taking this medication and discuss alternative options available to you.

Best of luck to you!

Jennifer R RPh www.drugstore.com




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