The MPV is marginally higher. This can be due to dehydration or an incidental finding. Repeat test after a week and see. If it remains persistently high, then it can be an inflammatory condition like rheumatoid arthritis. It is also increased in some bone marrow disorders like myeloproliferative disorders (polycythemia vera, essential thrombocytosis, idiopathic myelofibrosis and chronic myeloid leukemia). All known causes like myeloproliferative disorders of bone marrow, essential thrombocytosis, chronic myeloid leukemia, rheumatoid arthritis etc have to be looked into, and bone marrow biopsy performed. If these are ruled out then other rare causes need to be looked into. One is an absent spleen or a poor functioning spleen. A rare condition known as Kawasaki's disease, which occurs as a result of inflammation of the arteries is another possibility.
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