ADH/LCIS

[covertanjou]

I went in for my pre-op yesterday (will be having an excisional biopsy after having had a stereo biopsy), and was able to see my pathology report.  The report from my stereo biopsy states;  Lobular Intaepitelial Neoplaisa (ADH/LCIS Spectrum).  Fibrocystic changes with Adenosis, Columnar cell changes/hyperaplasia; Usual ductal hyplasia and Aporcrine metaplasia.  

Can anyone tell me what this means?  I understand that my samples shows ADH and LCIS.  What are the other things?  What are they looking for in the excision biopsy?

[Cleveland Clinic]

Dear convertanjou:  The conditions you mention in the report are mostly benign changes.  Certain benign changes such as ADH, LCIS and columnar cell changes, however, are associated with an increased risk of cancer. When these are identified, it is common to then do an excisional biopsy that removes the whole area of concern to be certain that there is not a cancer that that may have been missed on the needle biopsy.

[malloy0]

Hi,

My wife was recently diagnosed with ADH breast pre-cancer in her right breast. Today after an excisional biopsy last week, we learned she "has" LCIS. We realize this is stage 0 cancer and that specific "treatments" are to be discussed with our Doctor. What might be a good plan? My wife is 49 YO and her Mom was diagnosed with breat cancer and been in remission for the last 20 years.

We are thinking that we would not do anything with surgery, request 1 mamogram (mammogram) and 1 MRI annually and maybe, just maybe tamoxifen.

Would like to get an opinion on this plan? Is it a normal one? One that is too patient? Or?

Thanks,

m0

[krisc317]

Hello, I was recently diagnosed with LCIS as well.  I am 54 years old, with no breast cancer in family.  I have just met with the oncologist after all other diagnostic tests, and surgeries to make sure nothing invasive was there.  My oncologist said he would like to see me every 6 months and my breast surgeon the other 6 months.  He also recommended I start taking Evista.  He is not sure about me having yearly MRIs, but will meet with my breast surgeon and radiologist to see what they recommend.  I would prefer a yearly MRI and digital mammogram because the possibility of invasive lobular cancer really terrifies me.  As you probably know, lobular cancer does not usually show on a mammogram until it has grown quite large.  My oncologist was quite clear that he does not consider LCIS a breast cancer, just a marker to be watched a little more closely.  Truthfully though, LCIS scares me because there really is not alot of information on it, not a common finding. Good luck to your wife. I would love to connect with others facing this uncertain road.  I do have a friend who was diagnosed 11 years ago with LCIS.  She was only 36 years old and has had not other biopsies or problems of any type. She is just watched every 6 months with 6 month mammograms, and opted not to take tamoxifin (tamoxifen) or any other preventive drug.  Blessing to  your family.

[malloy0]

krisc,

We see our Onc tomorrow, Tuesday at 4pm EST. I will report back what he says. So far from a few others we have talked to, the general guidance, especially given the history of her mom's breast cancer is to do a masectomy for both breasts and then reconstruction.

We'll see.

Thanks,

malloy0