March 25, 2002 Ultrasound: 10x12 mm oval ecopoor nodule upper right breast, 12 o'clock position.
April 2002 Needle biopsy: "Infiltrating carcinoma which shows moderate nuclear pleomorphism, scanty mitoses and rare tubles corresponding to a grade 2 carcinoma. There are foci of mucinous differentiation, of calcificatgionn, of intraduct carcinoma, and of single file infiltration and intravascular growth."
Immunostaining: "Estrogen receptor (clone 1D5) showed strong staining. 90% of invasive tumor cells were positive. Progesterone receptor (clone PgP636) showed strong staining. 20% of invasive tumor cells were positive. An E-Cadherin stain is positive supporting a diagnosis of ductal carcinoma."
May 10 Chest X-Ray, Isotope bone and Ultrasound Abdomen tests all negative, including upper abdominal lymphhadenopathy.
My sister (45) has been advised to obtain a full mastectomy and auxiliary clearance by the same foreign hospital team that last year advised my youngest sister (37)with only DCIS to undergo the same prodeedure.
Questions: Based on current statistical data on survival rates, would a lumpectomy and sentinel node biopsy also be appropriate in this circumstance (given the available information) instead of the radical mastectomy? Would additional tests be necessary before making this decision? Would the information from the sentinal node biopsy be important for contemplating possible future actions, including more extensive surgery? Is it not appropriate to undergo a proceedure of whichever type on a timely basis