Breast Cancer Community
Lymph Node with Reactive Hyperplasia-Help?
About This Community:

This patient support community is for discussions relating to breast cancer, biopsy, genetics, chemotherapy, hormone therapy, lumps, lumpectomy, lymph node dissection, lymphedema, mammograms, mastectomy, radiation therapy, reconstruction, and self exams.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Lymph Node with Reactive Hyperplasia-Help?

I had a large Core needle biopsy done 2 weeks prior to surgery to my breast surgery for DCIS with a focus of less than 1mm of microinvasion, & a sentinel node was taken out for examination.
What does the information below mean.

My pathology report stated: Sentinel Node #1, Excisional Biopsy:
Touch Preparation Smear: No Malignant Cells Seen.
H&E Sections: One Lymph Node with Reactive Hyperplasia: No evidence of Metastiatic Carcinoma.
Cytokeratin Immunostain: No Evidence of Metastatic Carcinoma.

What is Reactive Hyperplasia? What causes it? Is this common?


Related Discussions
2 Comments
Blank
Avatar_m_tn
Hi there.

Reactive hyperplasia is a response of the lymph node to foreign antigens especially during infection or in cases of microinvasive disease from a DCIS.  The good news is that there are no malignant cells seen in the lymph node.  This is no cause for alarm but I still suggest that you have regular follow ups with your doctors or surgeon.  I would also suggest to discuss with your doctors regarding additional radiation therapy for your DCIS.  Check your breasts regularly from now on.  Regards and God bless.
Blank
Avatar_f_tn
Thank you for your prompt response to my question regarding Reactive Hyperplasia in the lymph node. I don't understand what the following statment means in your response "in cases of microinvasive disease from DCIS".  Should I be concerned with this even though there was no cancer detected in the node? Yes, I will be doing radiation (not chemo) and will have regular follow up visits with my doctors.  Thank You for your advice and if you can please clarify your response.
Blank
Continue discussion Blank
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Breast Cancer Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank
Top Breast Cancer Answerers
25201_tn?1255584436
Blank
japdip
587083_tn?1327123862
Blank
zouzi
961574_tn?1431661445
Blank
mhv
Lancaster, OH