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Severe Bouts of Fatigue

For several years now I've been taking Remeron, Paroxitine, Wellbutrin XL and Lithium; everything is at the top dosage. Only the Wellbutrin and Lithium I take during the day.   These drops have been going on for quite some time, but now are the very worst they have been.

Last year I had to quit a part time job because of this and got on the sub list.  Mornings are my best times til 9:30am,  I push myself thru chores and if I do go to work I pray that is only for 3.5hrs.

Things I do to help my weariness leave is to chew gum, stretch, eat a snack of apples and peanut butter.  Napping is not a option since I cannot sleep during the day and I do get restless once I'm laying down.

Please I'd appreciate any tips for handling severe daytime fatigue.   Thanks and nothing is too weird not to give it serious thought.
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596143 tn?1226648054
Years ago I was on Remeron and had to stop taking it.  I would take it at night and sleep so heavy that it scared finance'.  The house could be on fire and I wouldn't wake up.  I would be totally out for exactly 10-12 hours and wake up.  Yes, I would wake up refreashed, but It was too dangerous to for me to be in that deep of a sleep.  Plus, If by chance I did wake up, the next day I would not remember what I did while I was awake.  Make sure you look for those sypmtoms.  The remeron might be effecting your days.
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Avatar universal
I forgot to ask.... You do take your Remeron at night right?

One of the side effects of Remeron is about 3 to 5 hours of sleepiness after taken. After that point it actually works to combat the fatuge that severe depression causes.

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Avatar universal
When did you switch from SR to XL. That could be part of the problem. I took Remeron and felt groggy all day long every day and ate my way through all my groceries every few days.
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Avatar universal
Thank you so much for the suggestions.  I'm taking 30mgs Paroxitine, 30mgs Remeron and 450mgs Wellbutrin.  Wellbutrin is now SR as I cannot afford the XL and I'm taking all in generic form.

Again Thank You
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Avatar universal
I would also have to agree with remar. My guess would be the Paroxitine that may be causing this day time fatuge.

I am on a med combo very much like yours, and I swapped the Lexapro in favor of Prozac and have noticed much less day time fatuge.

This was my P-doc idea, he said that Prozac is a more energizing SSRI than Paxil or Lexapro. He was proven to be correct, as after 22 days on the prozac I have felt much less tired.

A couple months ago I also started getting Vitamin B-12 shots once per month. I'm not much for natural remidies, but these B-12 injections do seem to be having a positive effect on my day time fatuge. Prior to the shots, I was taking B-12 tablets, but they didn't do a thing.

Just some ideas to think about for you.

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Avatar universal
i take paroxitine too but at a very low dose and it still makes me tired. what dose are you on? you may need to cut way back on it. wellbutrin is a stimulating med so i don't think that's the problem. the other two i'm not sure about. i wish i could help more. i really think it's the paroxitine. check with your dr. before cutting down or changing any of your meds. take care. remar
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