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Paxil and Wellbutrin

I took Paxil for years and because of the sexual side affects I Switched to Wellbutrin XL 300 mg last year.  Recently my depression has started to come back and today my doctor added the Paxil 40 mg again and said this is a common pair because neither work long ter alone.  Has anyone used this combination?
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Avatar universal
I currently take 25th of paxil cr 24hr at night. It was seriously ruining my sex drive and the ability to finish. I KIM
Doc put me on 150 mg of wellbutrin xr 12hr which I take in the morning to counter that effect and it has worked for me. Only trouble is sometimes I will forget to take the wellbutrin and I get the brain zaps.  It messes with my head and lasts for days. I don't know if it's worth staying on the Well. just for sexual gratification.  I haven't experienced weight gain. But I do work out.
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Avatar universal
I have heard this is a common combination as well as is Wellbutrin with other medication. Right now I am tapering off Lexapro and starting Wellbutrin but the thing is I hesitate to take any SSRI (Wellbutrin is not an SSRI) because of the weight gain they cause. Paxil seems to have very bad sexual side effects and is the worst, in my opinion, for weight gain.

My husband has been taking Paxil since March and has gained a lot of weight. He was taking 40 mg and had severe sexual side effects. His dose was reduced to 20 mg and that seemed to do the trick for the sexual side effects but not the weight gain, which is still a problem. His appetite has gotten out of control too, as was mine when I used to take Paxil.

I finally went off Paxil several years ago and lost all the weight and my husband is going to try something else too when he sees the doctor this week.
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