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Avatar universal

Is melanoma simply a Vitamin D deficiency cancer?

Lately there's been some research speculating several cancers to be Vitamin D deficiencies, except for one: malignant melanoma.

Yet a deficiency in Vitamin D3 would affect the skin first and foremost, because it is the primary source when exposed to natural sunlight.  Moreover, a Vitamin D deficiency disease would affect all ages and both genders, unlike prostate, breast, and colon cancers for example, which largely arise in old age.  And besides, no cancer experienced such alarming growth as melanoma did during the sun-protective efforts of the past quarter-century.

So do you think that melanoma could stem from a deficiency in the "sunshine vitamin"?
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Avatar universal
A related discussion, melanoma and vitamin d3 mortality rate was started.
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Avatar universal
Saves youse from rickets too!
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125112 tn?1217273862
Just received this in my email and thought that you might be interested in it:

http://www.medicalnewstoday.com/medicalnews.php?newsid=51913

"A short while later, a group of scientists from UCLA published a remarkable paper in the prestigious journal, Nature. The UCLA group confirmed two other recent studies, showing that a naturally occurring steroid hormone - a hormone most of us take for granted - was, in effect, a potent antibiotic. Instead of directly killing bacteria and viruses, the steroid hormone under question increases the body's production of a remarkable class of proteins, called antimicrobial peptides. The 200 known antimicrobial peptides directly and rapidly destroy the cell walls of bacteria, fungi, and viruses, including the influenza virus, and play a key role in keeping the lungs free of infection. The steroid hormone that showed these remarkable antibiotic properties was plain old vitamin D."
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Avatar universal
Certainly the same sun, but the concentration of UV rays varies geographically. The potential highest UV concentration from living in Tuscon Arizona is far higher than in Liverpool because it is at a lower latitude - therefore the sun rays travel through less atmosphere and are concentrated over a smaller area (and therefore more intense). Hence places like Cairns which is the "Skin Cancer" capital of the world (combined with the fact that many white people live there).
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Avatar universal
Milk is not especially good for you. Staying out of sunshine completely is potentially harmful.

http://www.bbc.co.uk/science/hottopics/sunshine/benefits.shtml
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Avatar universal
Sun. Same sun in Liverpool as in Tucson. Spend a July in Tucson sometime and tell me about how much you love the sun...
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Avatar universal
Milk. Drink milk. Stay out of the sun. Ages skin prematurely.
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Avatar universal
Thanks for your comment.

I do not think that people who get chronic sun exposure are necessarily getting more Vitamin D.  Indeed, sunlight darkens and thickens the skin, which inhibits ultraviolet penetration.

Could the prevention of melanoma thus involve optimizing sun exposure in order to ensure a consistent, year-round supply of Vitamin D3?
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Avatar universal
Is it not a case of adequate sun exposure. I would assume that there is a negative correlation between "optimum" sun exposure and risk of melanoma. But I am just asssuming.....
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242489 tn?1210497213
MEDICAL PROFESSIONAL
If it did, wouldn't people who get a lot of sun exposure get less melanoma?  They get more.

Best.

Dr. Rockoff
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