Glipizide and weight gain

[Debora888]

Hi, I recently went on glipizide after a very bad reaction to victoza. I was losing weight, but now the glipizide is keeping me at the same weight. Has anyone had the experience that is the same? and is there a lower does that anyone has still been able to lose weight with?  and yes I'm on a low carb diet and excercise plan. I'm doing better with this than I did before and I lost 33 pounds. It's the glipizide. also when do people take there dose, I may cut down to one pill a day to see if its helps me. Thank u

[Debora888]

Well, victoza will start off making you have nausea, vomiting sometime.  You will get past this, it can take up to three months. After that I just kind of never felt right but thought I was just going to have to deal with this the rest of my life! Than about at 10 to 12 months I started to have severe stomach pain which I thought was my gall bladder. I was probably having pancreatic attacks, but never went to the hospital to have blood work; very stupid idea by the way. My PCP took me off victoza, and within a few days I felt like a completely different person. Now I'm not saying everyone will do badly on victoza, everyone is different. I wish you luck. It does help with weight loss. But don't suffer on this drug if it does not agree with you. Pancreatitis is nothing to fool with. Now since I posted my question I decreased my dose to once a day in the morning of glipizide and I immediately lost weight the next day. And I have lost .4 every a day doing this, so it does cause weight gain, but works well on my sugars and does not make me sick like every drug I've tried. I could cut it as long as I'm being good with my excercise, and low carb diet. I know how to lose weight, I've lost 30lbs last year. I think cutting my dose and doing this will work now. My sugars run between 90 and 140. I can live with this till I lose the rest of my weight. Also for all of you out there, I started cooking with protien powder; low carb. If anyone wants help with this let me know! well good luck!

I also did not do well with the Glipizide.  Eventually I went on 1000mg twice a day Janumet, and 2.5XL Glipizide, it worked for a while. I recently gained 8 lbs. but not sure it was the glipizide.  On my second day of Victoza, so far ok.  Interested to hear what kind of reaction you had to Victoza.