My reg family doc wanted me to go to see the gastro doctor to have an endo done back like 3 or 4 months ago when he had to switch me from protonix (which is my 2nd or 3rd med to try for acid reflux) to Nexium , the strongest dose 40 mgs I think. Well at the time I didn't have time to go see the gastro doc. But I had to go see a ENT because of an ear infection and he said my throat looked really irriated and I had better get my acid reflux checked out. Plus now I take Nexium and Zantac 150 otc. That's only temporary until I go to the gastro doc. But this worries me... regular prescriptions aren't helping. I also have to take Questran for irritable bowl. Do you think that is what is making me have severe heartburn? I am tired of being sick and have been tested for everything in the book. Feel free to read my posts in other forums. Here are the meds I am own - Questran - 1 packet for irritable bowl, Prozac for OCD, Allergy Injections, Methyldopa for blood pressure, and Trilipix for Triglycerides (nearly 1000), and Vitamin D. I am only 30!! I am overwieght but work hard to get rid of it with little or no results. They even checked me for Cushings. My TSH is low at 0.3 and I have a Goiter but no known thyroid problem. I have acne. Anyone know what could be causing my heartburn to be so severe?