4th generation ag/ab test

HI..
does anyone how reliable 4th generation ag/ab test??
and is it true its window period is 2 weeks??

[Brian123]

I know of no test that has a window period of 2 weeks.
From what I know,.they still ask people at risk to wait 3 months.Nothing has changed about that...am I right?

[TONY2007]

doctor of lab told me so..
about 3 months u talk about ...that for antibodies..
but this test doesn't test for antibodies..

i searched on google now and found info like this..
BUT i wanna b sure of what i read..

[Brian123]

Let me ask you a few questions:
A. What was the risk?

Now...
EVEN IF you were infected with HIV, antibodies need sufficient time to produce in the human body.
The natural course of antibodies usually runs 22-26 days, whereby the vast majority of persons infected with HIV would produce antibodies and go through what they call "seroconversion".
Testing at 2 weeks was and is useless, in my opinion.

No less, I am unaware of your potential risk. What is causing you to test? Do tell.

[TONY2007]

my freind ..
read my previous post!
this test doesn't search for ANTIBODIES...

[Teak]

Yes the test does test for antigen and antibodies. Vironostika® HIV Uni-Form II Ag/Ab
With the combined detection of HIV antigen and HIV antibody in one single test the 4th generation of HIV screening tests has come available.

It doesn't say the the test can detect within 2 weeks. It say within the acute window period.

[Brian123]

Fill me in...was I wrong in this situation?

[TONY2007]

about how many days??

53 days good period?

[Teak]

They say it can detect 12 days earlier.

[Brian123]

well, a 6 week test would give you an excellent indicator....but you should be waiting 3 months for any serious risk.
But I am not one for wandering through numerous threads.
If people on here stuck to ONE thread, it would make it a LOT easier to decipher the real problem.

[TONY2007]

"They say it can detect 12 days earlier.."
u mean they say its window period 12 days??

[Brian123]

No. That does not mean that the window period is 12 days.
It merely states just that...it can detect the HIV antibodies 12 days earlier than the 3rd generation. Either way, I would believe that the 3 month rule still applies.

[TONY2007]

so how accurate NEG result on 53 day for oral exposure?

[mike_no]

The right time for a (duo test) p24 AG + AB is 28 days.

IV gen HIV test = Duo test = III gen antibody test + P24 Ag detection

IV generation test (P24 Ag and AB test) taken at the 4th week is very reliable because if the body has not produced detectable amount of antibodies by that time and seroconverting the p24 (proteins) would be definelty be detected and if the antibody is produced Ab would be detected.

Let me elaborate,

a. If one has already seroconverted the 'Ab detection' of the test is active and still a  reliable result could be obtained (Usually,p24 ab could be detected from 5 - 14 days)

b. If the individual is seroconverting (it's rare at the 4th week,since the average time to seroconvert is 21 days) the 'Ag detection' of the test would be active and a reliable result could be still obtained

*  A duo test is meant for early detection of HIV, it's minimised the window prieod to 14 to 28 days after exposure

P24 antigen is a protein which is found in one's body (assuming the person's HIV infected) at about 14 to 32 days after the infection, after the above mentioned time period detectable amount of antibodies would aways be present in one's body and the P24 Ag would not show up any more hence a P24 Ag and Ab 1& 2 test is advised at the 28th day for early detection only

For some one with a real risk, a negative at 14 days on a IV gen test would have been very encouraging however it's warranted to be backed up with a final test at the 12th week.

Now, coming to you - You never had a risk to begin with and testing was not warranted at the first place, you can consider your result to be conclusive and move on.

[TONY2007]

thank u..
but tell me..what is the reference written in the paper 0-90 neg.....90-100 gray zone .....above 100 poz..

what this no for?

[mike_no]

"For some one with a real risk, a negative at 14 days on a IV gen test would have been very encouraging however it's warranted to be backed up with a final test at the 12th week"

Let me explain further, what I meant by that - At 14 days the P24 AG detection part of the test is active, which means if the person was really infected, the test would have detected p24 AGs (It's possible that p24 Ag might not be detected in some people even if they are infected). Hence, it's encouraging but not conclusive by any means.

Brian: Hope you're doing well, IV gen test at 14 days is not useless but not conclusive either.

[TONY2007]

u didn't answer me?

[mike_no]

Those are in regards to your readings and purely for lab use.

It means, if your blood report readings are between 0 - 90, you are negative.
90 - 100 - meaning that the result is ambiguous or indeterminate
above 100 - Positive.

Your reading has to be 0-90, cuz you never had a risk. Now stop it and go back to reality, you are okay.

[TONY2007]

thank u...

but last qu am guessing...
i know white tongue MUST NOT relate to HIV infection in all times..

BUT if this is related to...
that mean there is virus in blood and can b discovered,,
or it can happen in period window?