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1924838 tn?1326924691

HIV Viral Load testing in side window preoid

Can any of the pros on this fourm tell me if a RNA PCR real time viral load test would be accurate at 9-1/2 weeks post exposure to HIV? I had a viral load test done last week that was <20 copies/ml, HIV-1 RNA not detected.

I will test using an HIV anti-body post 90 days, but just want assurrence that if I would of been infected with HIV the HIV RNA PCR test would of should a VL count. I did have few ARS symptoms post exposure due to a condom break during sexual intercourse.
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Avatar universal
It would be very high.That's when a person is most infectious,just after they contract the virus.The HIV RNA by PCR is a good test at this time frame,but needs to be followed up with an antibody test at 3 Months.That is what your doing anyway.All the best.
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Avatar universal
PCR-RNA are supplemental tests they are used in conjunction with an antibody test.
Helpful - 0
1924838 tn?1326924691
Thanks. That is what the med clinic told me, but since I did/am having ARS symptoms they reccomended that I do a HIV RNA PCR Real Time viral load test. I requested for them to do a anti-body test but they stated that I needed to wait post 90 days. Today when I got my results back I requested a anti-body test, but they scheduled me to come back on my post 90th day to do the anti-body test. The doctor stated that it was a waste of time and money to do a anti-body test before 90 days post expose.

Would I have a readable VL 67 days post exposure if I would be infected with HIV? When I asked the Dr. he was not to clear in his remarks and stated that there was a 1% chance of results being a false neg/undetectable due to being an controller or the virus was reaching a low set point under <20 copies/mL with out being on ART.

Also, DR stated that the RNA PCR checks for all HIV-1 groups and subs, but does not check for HIV-2.

How common is it for someone to be a controller or for someone to have a set point VL under <20 copies during the first 90 days? I read your bio profile and it seems that you have vast knowledge in regards to HIV matters.
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Avatar universal
Get your conclusive test at 3 months.
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1924838 tn?1326924691
Does anyone have any info in regards to Viral Load count during the first 3 months of HIV infection? Would it be high and a certin point to flat out at another point during ARS and/or seroconversion?
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Avatar universal
NO, that is not necessarily true.
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Avatar universal
In majority of cases it would be.That's what the CDC says.
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Avatar universal
CDC says a lot of things that are not totally true and to say your VL would be high at 9.5 weeks is not totally correct.
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1924838 tn?1326924691
Teak, what are the reasons behind you last comments about getitright77's comments on the HIV viral load in the first 3 months. Please advise.
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Avatar universal
Not all people that are infected show high VL. That's why PCR-RNA tests cannot diagnose primary HIV infection. Elite Controllers and LTNP rarely have high VL.
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Avatar universal
My Hiv expert friend in sydney says that the viral load of a person just recently infected is usually quite high.Even our expert doctors say the HIV RNA is very reliable early on.
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1924838 tn?1326924691
What is a LTNP and why would they not have a VL >19 copies/mL?
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Avatar universal
Long term non progressor..
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Avatar universal
For example people like Magic Johnson are LTNP's.
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Avatar universal
Because their immune symtom can control the virus replication.
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Avatar universal
Just wondering why you didn't have a DUO test at the 4 week mark.Most people have detectable p24 antigen by then.
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Avatar universal
Limitation of 4th generation tests.  A negative test result at any point in the investigation of individual subjects does not preclude the possibility of exposure to or infection with HIV-1 and/or HIV-2.
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1924838 tn?1326924691
So I would be currently HIV+ and since my VL was undectable this would mean I would ether be a elite controller or a LTNP?

Hofully my 13 week HIV 1/2 anti body test will be neg.

I had just about every ARS symptom, but did not have Fever, no Sore Throath, and no swolllen lymp nodes.

Lost 6% of body weight (12 lbs) in six weeks.

Only odd thing was that all the symptoms did not come at the same time and do not dimimish  at the same time. Is this common in ARS?
Helpful - 0
Avatar universal
PCR-RNA cannot give a negative or positive diagnosis.
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1924838 tn?1326924691
Currently I was told that a DUO p24 was unavailble and not FDA approved. I was told to wait to 90 days until an accurate HIV anti-body test would be 99.9% conclusive.
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Avatar universal
These two are FDA approved;

ARCHITECT HIV CMIA TEST 6-18-2010
BIO-RAD GS HIV EIA TEST   7-22-2011
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1924838 tn?1326924691
Is there a National lab that i can test with a DUO? As my doctor told me it was not yet approved in the USA.
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Avatar universal
NO, I wasn't on meds for 21 years.
Helpful - 0
Avatar universal
Your wasting your time with the DUO now,it is only good from 1 to 4 weeks after exposure.Just have an antibody test and you will be fine.Your doctor is wrong.DUO tests are approved in the US.They have been since 2010.
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