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Question on seroconversion - would greatly appreciate your feedback

I have a question on late seroconversion (post 12 weeks) if it even occurs.

I have read infinte times that people do not need to test beyond 12 or 13 weeks for HIV if they are negative.  But I am just trying to understand for the people who do such as - 'severe immunosuppressed' or chemo treatment patients.

1.  Can anyone give me an example of what people with 'severe immune disease' suffer from, and their need to test beyond 12/13 weeks?  

2.  Is possible that someone who is suffering from cancer, but is not on treatment of any kind, or not on chemo., can delay seroconversion for HIV?

3.  Does Co-infection with HCV/HIV delay seroconversion too?

Just want to say that this is not for me, but I'm trying to understand something here so please be serious when responding.  I've read messages from members here but don't seem to get answers to these two questions.

Everyone, your feedback is greatly appreciated!  Thanks for reading.
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Avatar universal
That will be up to the advice of their doctor.
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Avatar universal
This is fantastic!!  This was indeed extremely useful information from both of you.

Teak, THANK YOU (again) for those much needed links.  It was very useful learning about these.  

Just one question, People who have a very severe case of such diseases, do they wait 6 months or up to a year for the testing of HIV?
Helpful - 0
Avatar universal
Nervouskid, there are apx 100 immune deficiency diseases. Here is a link that You can read on causes of immune deficiency in which you will also find autoimmune disease. Note that one has to be severely compromised to prolong and possible late seroconversion

http://www3.niaid.nih.gov/news/newsreleases/1997/pid.htm
http://www.primaryimmune.org/pubs/book_pats/e_ch01.pdf


X Linked only affects males. Which is only one of the causes for immunological diseases.

Complement deficiencies usually involve an absence of one or several of the proteins that contribute to the complement system’s ability to attach to antibody-coated foreign invaders. In childhood or early adulthood, a complement deficiency can result in severe infections such as meningitis, or it can contribute to an autoimmune disease such as lupus erythematosus.

(http://www.niaid.nih.gov/publications/pdf/ADCCFinal.pdf) link to autoimmune disease

Some Causes of Immune deficiency
http://www.wrongdiagnosis.com/symptoms/immune_deficiency/causes.htm

Helpful - 0
219662 tn?1223858560
Teak is wrong on this one.
"Disease that causes the body to produce antibodies that attacks its on tissue" - that's called autoimmune disease, not immune disease.  These diseases do not affect antibody production.
What I think you are referring to is "immune deficiency".
There are many such disorders, X-linked agammaglobulinuria for one.
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Avatar universal
Hi everyone...

anyone want to extend responses in this thread?  Thanks for reading.
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Avatar universal
You're right.  But this was not in relation to me and my negative result at week 12/13.  I'm trying to understand something here.  Sure if one was severely immunosuppressed the person would be in hospital, and that's all logical, but I'm trying to get an idea or an example of this severe condition, if any of you can shed some light on.  That would help.  Also, how much longer does that person have to test out to -  6 months or to a year?
Helpful - 0
Avatar universal
Like you mentioned nerviouskid (*nervous), cancer and chemotherapy patients are excellent examples of immunosuppressing conditions. They have to be pretty darn serious to delay seroconversion, and if you had one of the immunosuppressing conditions, you would most likely be in a hospital right about now.
Helpful - 0
Avatar universal
Thanks for the reply Teak.  

Do you mean that any disease that attacks body tissues after producing antibodies?  Just want to be clear.  I'm not sure if you can give me an example of one....it would help.

Also, do such people test out to a year or would 6 months be sufficient for them?  
Helpful - 0
Avatar universal
1.) it's any disease that causes the body to produce antibodies that attacks its  on tissue.
2. No
3. No
Helpful - 0
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