Aa
How to dissolve Atherosclerotic plaques?
Does endogenous bile salt dissolve Atherosclerotic plaques?
How?
Any other modes of treatment to dissolve Atherosclerotic plaques?
How?
Any other modes of treatment to dissolve Atherosclerotic plaques?
Thanks. What about EDTA?What is the overall credibility of chelation therapy?
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"smooth them, much like a sander.smooths"
A bit of a basic description :) but not really practical. The problem is, the lining is made from living cells and you can't just split a cell in half to align it to the cell, or missing cell, next door.
I think maybe a better solution would be to use the bio degradeable stents which are coming up. A long stent could be inserted into the rough artery, the longer the better because it would require less pressure to hold it in place, it would be less likely to slip.
After three months or so, a nice smooth lumen should have grown and the stent will have dissolved. Eh Voila, a nice new smooth lining.
This is the way stenting is supposed to be aiming in the near future, but I think it will require many cardiologists to alter their methods of practice. Let me explain...
My first stent was due to a clot which was ruptured plaque in my obtuse marginal (OM1).
The cardiologist removed the plaque and most of the clot, leaving only a small amount of soft fat. The stent was then inserted and it only had to squeeze against a small amount of soft material. The same happened with my LAD in September 09. The cardiologist obliterated the plaque using different tools, leaving only the smallest amount of fat in a few areas. 5 long stents were implanted which again ended up having to only squeeze a small amount of fat. My stents are concentric in the arteries and are not causing untold damage to the lining. Now this, from what I have been reading, is not always the way of practice. It would appear some cardiologists simply squeeze a stent against the hard plaque, forcing it into the artery lining. Some plaque can be like soft chalk, but it can also be much much harder. Imagine what it must be like when a Cardiologist squeezes rock hard plaque which is irregular in shape, into the artery lining. It will not squash down, it will put a lot of extra strain on the artery, forcing the wall outwards and the plaque will probably cut into it. Also, the stent will unlikely be concentric in the artery.
If bio degradeable stents are to be of useful benefit, then all the plaque will have to be removed and a good portion of the fat. Maybe this is why they are taking so long to come into play, because I know the stents have existed for some time now.
A bit of a basic description :) but not really practical. The problem is, the lining is made from living cells and you can't just split a cell in half to align it to the cell, or missing cell, next door.
I think maybe a better solution would be to use the bio degradeable stents which are coming up. A long stent could be inserted into the rough artery, the longer the better because it would require less pressure to hold it in place, it would be less likely to slip.
After three months or so, a nice smooth lumen should have grown and the stent will have dissolved. Eh Voila, a nice new smooth lining.
This is the way stenting is supposed to be aiming in the near future, but I think it will require many cardiologists to alter their methods of practice. Let me explain...
My first stent was due to a clot which was ruptured plaque in my obtuse marginal (OM1).
The cardiologist removed the plaque and most of the clot, leaving only a small amount of soft fat. The stent was then inserted and it only had to squeeze against a small amount of soft material. The same happened with my LAD in September 09. The cardiologist obliterated the plaque using different tools, leaving only the smallest amount of fat in a few areas. 5 long stents were implanted which again ended up having to only squeeze a small amount of fat. My stents are concentric in the arteries and are not causing untold damage to the lining. Now this, from what I have been reading, is not always the way of practice. It would appear some cardiologists simply squeeze a stent against the hard plaque, forcing it into the artery lining. Some plaque can be like soft chalk, but it can also be much much harder. Imagine what it must be like when a Cardiologist squeezes rock hard plaque which is irregular in shape, into the artery lining. It will not squash down, it will put a lot of extra strain on the artery, forcing the wall outwards and the plaque will probably cut into it. Also, the stent will unlikely be concentric in the artery.
If bio degradeable stents are to be of useful benefit, then all the plaque will have to be removed and a good portion of the fat. Maybe this is why they are taking so long to come into play, because I know the stents have existed for some time now.
"The lining of the artery will be a real mess, all humps and bumps where the disease was. Of course this would heal over time, but good anticoagulant will be needed to stop further clotting."
It is interesting how the thought patterns of two people who don't know each other from Adam will sometimes match purely at random. I was performing a thought experiment (i.e. woolgathering) about this exact scenario just the other day. It seems to me that the result of merely dissolving the cholesterol, plaque and whatnot from the inside of arteries would be markedly similar to what happens when you clear a clog out of old PVC drain pipe. I've worked with the stuff for years, and have noticed that old pipe is scored and pitted on the inside by impurities caused by whatever gets washed down the drain over the years. Merely clearing out the clog wouldn't remove these imperfections, and in the case of your arteries, they would become an attractant for clots and provide a perfect base surface for further deposition of material.
I suspect that nanotechnology will eventually become part of the treatment of choice for this issue. After a good dosing with some sort of X-factor "unobtainium"-based flushing agent to remove plaque, nanites could be released that would travel in the bloodstream to the site of arterial imperfections and smooth them, much like a sander.smooths a rough piece of wood. And being on a microscopic level, the "sawdust" left over from this would easily be absorbed by the body just as it would any other small foreign object, and not create an additional danger of stroke.
While such technology won't happen in my lifetime, perhaps my family's spotty history of heart health or lack thereof won't be an automatic given for my descendants.
It is interesting how the thought patterns of two people who don't know each other from Adam will sometimes match purely at random. I was performing a thought experiment (i.e. woolgathering) about this exact scenario just the other day. It seems to me that the result of merely dissolving the cholesterol, plaque and whatnot from the inside of arteries would be markedly similar to what happens when you clear a clog out of old PVC drain pipe. I've worked with the stuff for years, and have noticed that old pipe is scored and pitted on the inside by impurities caused by whatever gets washed down the drain over the years. Merely clearing out the clog wouldn't remove these imperfections, and in the case of your arteries, they would become an attractant for clots and provide a perfect base surface for further deposition of material.
I suspect that nanotechnology will eventually become part of the treatment of choice for this issue. After a good dosing with some sort of X-factor "unobtainium"-based flushing agent to remove plaque, nanites could be released that would travel in the bloodstream to the site of arterial imperfections and smooth them, much like a sander.smooths a rough piece of wood. And being on a microscopic level, the "sawdust" left over from this would easily be absorbed by the body just as it would any other small foreign object, and not create an additional danger of stroke.
While such technology won't happen in my lifetime, perhaps my family's spotty history of heart health or lack thereof won't be an automatic given for my descendants.
I am very surprised that a dissolving agent hasn't been developed for this. Imagine having a cath done, but instead of applying contrast, a powerful dissolving agent is put into the coronary arteries. This would clear not only the major coronary arteries, but work its way down into capillary level. However, the danger is what's left behind, the soft mess hidden under the plaque. This is a mixture of pure fat and several other cells which have become stuck. This is the really dangerous stuff to the system. So, stage two would be some kind of powerful emulsifyer to dilute the fat into the blood. I wouldn't fancy the idea of this diluted fat going through the rest of my body, it could end up making a mess somewhere. I would have thought this process would require a rinse and quick removal using suction. Of course there then follows another problem. The lining of the artery will be a real mess, all humps and bumps where the disease was. Of course this would heal over time, but good anticoagulant will be needed to stop further clotting. Will other cholesterol lipids get stuck into the damaged wall and start atheroscerosis all over again? probably.
So no matter how you aim at it, the problem looks as though it will return.
So no matter how you aim at it, the problem looks as though it will return.
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