I have high blood pressure and have experienced palpitations. I had an echo two years ago, which showed borderline global hypokinesis, an EF of 53%, and trace mitral and tricuspid regurgitation. So my cardiologist put me on bp medicine. I had issues again this past April and had a nuclear stress test, which came back normal. To help with anxiety, my cardiologist took me off an ACE inhibitor and put me on 12.5 mg of carvedilol twice a day, in addition to 12.5 mg HCTZ. I overcame my anxiety issues with exercise and have been running 3 miles a day for the last six months. I recently had palpitations after running. I went to see the cardiologist just to be on the safe side. He heard a slight murmur, which was new, so he ordered another echo. He decided to put me back on the treadmill. The stress test was normal. The echo was not perfect, but good. My EF was better, 63%. There were no signs of global hypokinesis. There is mild-moderate tricuspid regurgitation. RV systolic pressure is 17 mmHg. Tricuspid regurgitant velocity was 1.7 cm/s. Also, there is mild enlargement of my RV and LV chambers. My cardiologist did not seem alarmed and told me to go back to running and come back in three months with bp measurements. My bp was a little high from not exercising: around125/85. But after exercising for the last week and being less stressed out, it is back down to 115/75. My questions are this: is running while taking beta-blockers a bad idea? Sometimes in the afternoon, it is hard to keep my heart rate up; am I making my heart work too hard? Also, should I be alarmed at the mild-moderate tricuspid regurgitation? I would think that after consistently taking my bp meds and getting 200 minutes a week of aerobic exercise, my heart would not start developing abnormalities.