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After effects of stopping tenoforvir
Please help. I have been on tenoforvir alone for the past one year. Eleven days ago i suddenly stopped bc of lack of supply.I want to knowt he side effects of stopping tenofovir. i get the feeling sometimes that am going to pass out and confused. Is this bc i sudeenly stopped. Before starting treatment, i didn't feel any pain around the liver area, during the treatment and even now am feeling pain.Is this pain bc of the treatment> maybe i should never have started in the first place.
as you advised i did some test. i asked for ALT/AST but i got my results as SGPT and SGOT. what's the difference?results are as follows
SGPT 11IU/L normal range 1-40IU/L
SGOT 10IU/L normal range 1-40IU/L
HepatitisB surface Ag 2468.85 S/CO Non-reactive:1.0
Interpretation: reactive
can any one help me interpret thsi results...note. I have been on tenoforvir for the past 1year,I stopped 6 weeks ago. bfefore medication my liver function as normal , i i didn check the Hbsag is it helping>??? i intend to continue by the end of month
SGPT 11IU/L normal range 1-40IU/L
SGOT 10IU/L normal range 1-40IU/L
HepatitisB surface Ag 2468.85 S/CO Non-reactive:1.0
Interpretation: reactive
can any one help me interpret thsi results...note. I have been on tenoforvir for the past 1year,I stopped 6 weeks ago. bfefore medication my liver function as normal , i i didn check the Hbsag is it helping>??? i intend to continue by the end of month
as you advised i did some test. i asked for ALT/AST but i got my results as SGPT and SGOT. what's the difference?results are as follows
SGPT 11IU/L normal range 1-40IU/L
SGOT 10IU/L normal range 1-40IU/L
HepatitisB surface Ag 2468.85 S/CO Non-reactive:1.0
Interpretation: reactive
can any one help me interpret thsi results...note. I have been on tenoforvir for the past 1year,I stopped 6 weeks ago. bfefore medication my liver function as normal , i i didn check the HBVag. is it helping>??? i intend to continue by the end of month
SGPT 11IU/L normal range 1-40IU/L
SGOT 10IU/L normal range 1-40IU/L
HepatitisB surface Ag 2468.85 S/CO Non-reactive:1.0
Interpretation: reactive
can any one help me interpret thsi results...note. I have been on tenoforvir for the past 1year,I stopped 6 weeks ago. bfefore medication my liver function as normal , i i didn check the HBVag. is it helping>??? i intend to continue by the end of month
Devedander.This is the truth and we must accept it. The chances of getting to negative is so low that i don't nurse such hopes.I have conditioned myself to live a healthy life. I know the virus is not going any time soon. and pray that a cure be discovered in few years to come.
My doctor has made it very clear to me that while this drug is excellent at surpressing viral load, the chances of sero converting (the real "cure") are very low... I think something like 30% in whites and much lower in Asians (do not go off my numbers, thats just the best I can recall). and has been very careful not to get my hopes too high... I think part of that is just making sure not to built false expectations (promise low in hopes of delivering high) but the numbers I have been quoted make me think you should expect to be on tenofovir for the long haul and if you clear or sero convert it's like hitting a lottery or jackpot....
Sorry to say to you and hope I am wrong on that for your benefit...
Sorry to say to you and hope I am wrong on that for your benefit...
good one Devedander what if you are pregnant and they say a pregnant and breastfeeding woman can't take tenoforvir?????i really want to know how long i will be on this medicine. i should have asked this before starting. I was told by my Dr that i can achieve clearance within 3yrs but at that time i thought clearance meant cure. I got it all wrong.
Sorry to hijack this thread but it got me wondering... what if you are very ill (lets say flu) and can't keep anything down for a week... which means you can't keep your tenofovir down...
This scenario doesn't seem terribly unlikely over a 10+ year process - what happens in cases like this where you are off the drug for prolonged periods?
This scenario doesn't seem terribly unlikely over a 10+ year process - what happens in cases like this where you are off the drug for prolonged periods?
please stef2011, u said in your above comment that elevated ast/ alt the better chances of clearance. Can you please throw more light on that? and also why do i feel pain below my right rib when on treatment? before treatment no pain and even after stopping treatment i still feel pain?
please stef2011, u said in your above comment that elevated ast/ alt the better chances of clearance. Can you please throw more light on that? and also why do i feel pain below my right rib when on treatment? before treatment no pain and even after stopping treatment i still feel pain?
The itches are not caused by tenoforvir. one of the symptoms of hepatitis is itchy skin.The only symptom i have now that i didn't have before starting tenofovir is pain below my right rib.
Thats kinda scaring yourself too much. Why would TNF induce autoimmune hepatatis? If it was IFN then yeah crazy stuff can happen.
i read somewhere that it is bc ur antibodies are making mistake and attacking healthy cells that look like the virus same like when someone has an auto immune disease . it was so scary.
that means we have to accept it so long as we have this virus. Thanks for your contribution
I have itching regularly. when i discussed with doctor he said its because of your liver making more extracts of billirum and SGPT.
Are u also experiencing itches? Ever since i got this virus my body has been itching.the situation become worst during flare-ups? right now ma taking vitamin D3. once i was on milk thistle. I have not don any test as of now.
Ok. Find my latest resuts below:
HBSAG (CMIA): 15,000 IU. HBDNA: Undetectable. HBEAG: Negative. HBEAB:Positive. SGPT (ALT): 94 and SGOT (AST): 40. Have been taking TNF for almost 2 years now.
My plan is to keep monitoring HBSAg levels every 3 months and when i have a decline below 10,000 i'd then start INF.
Meanwhile i also take Simvastatin with TNF daily with vitamins. I plan to order Heptech products to help protect my organs from any adverse effect of prolonged treatment with TNF. I wil advise you to also follow that route.
Finally, i believe that in the upcomming months, newdrugs which will clear the HBSAg for good will become available.
For me, Taking TNF in the meantime is the safest thing to do.
HBSAG (CMIA): 15,000 IU. HBDNA: Undetectable. HBEAG: Negative. HBEAB:Positive. SGPT (ALT): 94 and SGOT (AST): 40. Have been taking TNF for almost 2 years now.
My plan is to keep monitoring HBSAg levels every 3 months and when i have a decline below 10,000 i'd then start INF.
Meanwhile i also take Simvastatin with TNF daily with vitamins. I plan to order Heptech products to help protect my organs from any adverse effect of prolonged treatment with TNF. I wil advise you to also follow that route.
Finally, i believe that in the upcomming months, newdrugs which will clear the HBSAg for good will become available.
For me, Taking TNF in the meantime is the safest thing to do.
thanks for your reply. i stopped because the drugs was in shortage i will start back on the 13th. thanks for sharing your expereince with me. what are ur lastest test results??
Hi Nic2012. I have been on TNF for almost 2 years now. also feel the sensation around the liver area which i never felt before the treatment. I understand it might be some immune response.
Stopping has to have a basis. Either your HBSAG has become low enough for your immune system to finish up the clearing (less than 1500iu/ml depending again on ur genotype) or ur HBSAG has become negative and of course u have positive hbsag. Furthermore if you have to stop for other reasons then it has to be done gradually, and of course requires close monitoring. I will suggest u go back to taking TNF as soon as u can.
Stopping has to have a basis. Either your HBSAG has become low enough for your immune system to finish up the clearing (less than 1500iu/ml depending again on ur genotype) or ur HBSAG has become negative and of course u have positive hbsag. Furthermore if you have to stop for other reasons then it has to be done gradually, and of course requires close monitoring. I will suggest u go back to taking TNF as soon as u can.
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do not stop and restart tenofovir again in the future and always get 1 bottle of tenofovir extra stored for emergency, even missing the pills is very danagerous, this way you can develop resistance or rduced response to tenofovir.if the drug cannot be taken continuatively without any stop it is best not to take it, a resistance mutant to tdf can be much worst than staying of therapy
also che your ast, alt, hbvdna and possibly hbsag.some clear hbv stopping tdf but you need to check the following to know if you are among them:
hbsag quantity on the decline
hbvdna, doesn t matter, can be any number
ast, alt elevated, the more elevaed the better to clear hbv
it sounds crazy a stupid drug like that can have storage, i see you are in LA..i may understand this for one of the poorest third world countries not LA