Are seroconverted people still at risk of reactivation in old age?

[itac]

People who seroconverted but still have cccdna in their cells, can the virus become harmful again as they age and their immune system weakens? Will the surface antigen antibodies won't be able to neautralize the virus practices? Any studies made on this population to see what risk remains? I know I'm thinking way into the future and the first thing that needs to happen is being able to seroconvert, but thinking even then you're not completely off the hook with this virus. Hopefully they'll be able to target cccdna in few years too so it won't be a problem in old age.
What do you think?

[itac]

https://news.tracs.unc.edu/index.php/translational-news/nc-tracs-news/802-can-gene-editing-tools-cure-chronic-hepatitis-b

This looks promising, but far from clinical use... Also how you deliver CRSPR to every liver cell, delivery method might be tricky once they perfect CRSPR to cut out the cccdna.

[Royal36]

Wa if you take it with! The meaning of cure word it changed then may be functional cute ?

[Airquake]

A few weeks ago I had an appointment with one of the top professors in Poland specializing in HBV. He said the people may seroconvert but they will never get rid of it. You may be "cured" but you will take it with you to the end. Don't worry too much and live"r" your life.

[Liverpatient]

Unfortunately, this is how I see it: as long as the major culprit of the hbv infection, i.e. the cccDNA exists in the liver cells, the infection is always there. In other words, no cure before the genomic reservoir of the hbv, i.e. cccDNA is totally eradicated. What is so surprising is that there are almost no pharmaceuticals working on drugs that mainly target the cccDNA which is the main reason for the persistence of the infection.

[Bm2016]

i don't think old age is a problem as much as immune system being suppressed due to medical conditions such as cancer, chemo, steroid, my dr told me in that case, just need to retake viread again during immune suppression period.

[itac]

Can your immune system be suppressed not because of medical conditions but just old age? Isn't it weakens when you age regardless of medical conditions? If that's the case, wouldn't a mean you'll need to take it the moment immune system can't handle it anymore by itself all the way till you die?