Hep-B virus going increases continuously and showing a very high load of virus

[Shirazz]

Hi, i am infected with Hep-B virus and I know this about 2 yrs back, when i was going to donate blood.
After knowing this I do my various tests with the passage of time like
• LFT, CBC, ALT, SGPT, Diabetic, Blood Cholesterol, Lipids, ESR etc…
and my all tests were normal (with-in range) every time when i take that tests.

Although my other tests and my routine life is normal but the Hep-B virus going increases continuously and showing a very high load of virus. Current value of my HBsAg is
• Cutoff rate – 1.00
• Patient rate – 3753.02
I am very depressed as am didn't face any health problems before. I am software professionals and due to work pressure am couldn't able to have the proper diet and sleep as well but now if it’s necessary I’ll try to do this.

My question is what is the chance of becoming negative? Will it take years or virus will be in my body for life long?
Due to that I am still got much scared and couldn’t able to concentrate on carrier as well. Could you please let me know what needs to be done in order to get rid of this virus and to become negative.
I am doesn't have any habits like smoking or drinking.
Please let us know the diet plan so that we can continue having that in our regular lifestyle.

[stef2011]

Cutoff rate – 1.00       Patient rate – 3753.00
not helpful for cronic carriers, as said you have to make abbott it has result in iu/ml and low range 0.05iu/ml

TRIGLYCERIDES             <200                                    90 mg/dL
try to keep this as low as possible by omega 3 fish oil and diet, the virus uses lipids for the envelope and maybe keeping low cholesterol/glucose and trygl we get it weaker maybe not but it is a healthy measure anyway.in vitro low cholesterol at cellular level (not only blood) and insulin prevent secretion of hbsag and virions, also delivery of unsaturated acids by liposoms, which reaches the highest levels of absorption, showed a strong antiviral effect

cholesterol is good, try to decrease ldl more by diet or low quantity of red yeast rice, it contains lovastatin a natural statin that showed decreased cholesterol very much, if you take red rice monitor alt/ast closely
your hdl is low it must be hgiher than 50 and fish oil increases hdl and lower trygl, docosahexaenoic DHA      min  1 g        max     1.8g
eicosapentaenoic acid EPA  min 1.5 g       max   2.7g
if fish oil has less dha,epa it is useless or almost useless

HBV DNA Quantitative Detected    2.1 x 106 Copies/ml
see if it gets lower with diet changes

you might try alinia for now and see if hbsag gets lower and hbvdna stays und

[Shirazz]

Plz check my reports. I have taken each test 2-3 times during last two years and the results were within the normal range. And plz tell me if u required any other test for dictating me, I will be providing you that as soon as possible. I am not using any medicine till now.

HBsAg (5th Feb 2011)
Cutoff rate – 1.00       Patient rate – 3753.00

ESR (5th Feb 2011)
Normal Range(s)       Patient =5 mm/1st hr

Lipids (5th Feb 2011)       Normal Range                Patient Value
TRIGLYCERIDES             <200                                    90 mg/dL
CHOLESTEROL              <200                                    170 mg/dL
VLDL                               0-40                                    18 mg/dL
LDL CHOLESTEROL        <130                                   111 mg/dL
HDL CHOLESTEROL       35-65                                    47 mg/dL

CBC (Oct 2010)         Normal Range                    Patient Value
WBC                            4 -11                                  5.31  x10.e 3/µl
RBC                             4 – 6                                  5.08  x10.e 6/µl
HGB                            11.5 – 17.5                         16 g/dL  
HCT                             36 – 54                               47 %
MCV                            76 - 96                                92.5 fL
MCH                            27 – 33                              31.5 pg
MCHC                          33 – 35                               34 g/dL
%RDW-CV                   11.5 – 14.5                         13.2 %
PLT                              150 – 400                           231 x10.e 3/µl
MPV                             7.2 – 11                              11.8 fL
%Neut                          40-75                                 63.3 %
%LYMP                        20-45                                 20.3%  
%MONO                       2-10                                   9.2 %
%EOS                           0-6                                      6.8              
%BASO                         0-1.5                                   .4 %
#NEUT                          1.9-8                                  3.36 x10.e 3/µl
#LYMP                          0.9-5.2                               1.08 x10.e 3/µl
#MONO                        0.16-1                                .49 x10.e 3/µl
#EOS                            0-0.8                                  .36 x10.e 3/µl
#BASO                          0-.2                                    .02 x10.e 3/µl

Chemistry – I(Oct 2010)     N-R                          P-V
UREA NITROGEN             6-20                  12.2mg/dL       
CREATININE        0.70-1.20   .86 mg/dL
GLUCOSE (RANDOM)      70-170    77 mg/dL
TOTAL BILIRUBIN        upto 1.0    .35 mg/dL
ALT                10-50    21 U/L
AST                10-50    29 U/L
ALKALINE PHOSPHATESE 40-129    96 U/L
GGT                   8-61    10 U/L
TOTAL PROTEIN   5.5-8.0            7.6 g/dL
ALBUMIN                   3.5-5.5   4.47 g/dL
GLOBULIN           2.0-3.5   3.13 g/dL
A/G TATIO                        1.43

HBV DNA Quantitative Detected    2.1 x 106 Copies/ml   (Sep-2009)

[stef2011]

So it’s not an issue if HBsAg increasing continuously?
it is an issue but only when the number is in iu/ml it shows hbsag quantity, we cannot say it is increasing wih the results fro other tests

And what should I do to rid off or decrease its level, any change required in my life style, diet or any preventive measures?
there are few drugs that lower hbsag and on few patients now, these are interferon, alinia (nitazoxanide).both drugs can have more responders with vitamin d level 50-60ng/ml (95% hbvers are vit d deficency).

what drugs are you taking?post all your tests results to say if drugs are needed

Please tell me and if any other test required?
hbsag with abbott might tell us if interferon/alinia can have good results, hbsag<1500iu/ml have high seroconversion rates on responders

[Shirazz]

Thanks for the time.
So it’s not an issue if HBsAg increasing continuously? And what should I do to rid off or decrease its level, any change required in my life style, diet or any preventive measures?
Please tell me and if any other test required?

Is this any test "abbot architect with unit iu/ml cut off 0.05iu/ml "

[stef2011]

• Cutoff rate – 1.00
• Patient rate – 3753.02

this hbsag test is not quantitative and this number 3753.02 is just reagent that gets in the positive range, so it is not possible to say if it is increasing and how much, although more reagent might be more hbsag

you have to test with abbot architect with unit iu/ml cut off 0.05iu/ml

also consider that liver damage is made by hbvdna only, hbsag just suppresses immune system.an hbsag increase might reflect more infected cells but absolutely not more damage, there is no correlation between infected cells and liver damage