https://www.youtube.com/watch?v=JWWMYe-h3YA
this is something to think about...
Is this it for sale? http://www.invivogen.com/imiquimod-vaccigrade
looks like it is available as an injectable too
Next time that will most likely be phase 3... when they won't care if you were treated or not..
DJ... do you still think this is medicine? I mean HOW may stipulations and criteria we must meet? Do they realize other there at Gilead what we live with?
They should just give it to people that want to try it. For god sake! if this thing makes our own interferon, to which there is no resistance, there is really No point in taking nucs, and it should not matter, whether one is VL positive or undetected, treated or naive, since the virus never develops resistance to interferon. All these trials are set up to just inflate the cost of healthcare, nothing more..
Another thing, is that they only give this medication for 5 weeks, And I don't know if this is enough time for most people..
Anyway, as it is based on what I seen this trial gets a thumbs down from me.. to may hurdles to jump over for a sick patient..
congrats, keep updating status.
dont be discouraged. try next time with better luck.
they said I could be in the trial if I wanted = currently taking TDF. Just have to have HBVDNA Und for 6 months or longer
placebos are going on, mostly because of tradition and old school thinking.
placebo is really an old fashioned and outdated concept. and it seems anti-humanity and in most of the trials(absolutly not all trials) it is not required and is useless.
veteran : As for placebo use in chronic hbv subjects. It is unethical.
exactly, placebo must be unethical, what is the need to do placebo every time? once they know natural history of a desease, there is absolutely no need to do placebo every time.
placebo is centuries times old concept of medicine, when it was required because at that time very less was studied and documented on natural histories of deseases. nowadays most of the deseas's natural history is well documented in scientific literature and easily available.
placebo may be allowed in deseases where new blood test or monitoring parameters emerged with time (as hbsag in hep b which was not approved before),which were not available before. in these cases placebo may be allowed but otherwise it should not.
please inform us, about this new GILEAD sponsored trial. what is it about, gs-9620 or some other compound?
As you visited the GS9620 cinical trial center do you have any update about the trial
Yeah we desperately need an alternative solution to big pharma. China and Russia yes with state runned health care can make a difference. But I don't see.so far any big push towards that.
These projects are need to be undertaken under government control. Otherwise look what have the private companies have turned it into. An industry for everyone to make money playing the system.
As for placebo use in chronic hbv subjects. It is unethical. It is known that imiquimod works against many viruses. They know it from animal testing and preclinical trials. If they did not know it would not go into trial.
With us it is just relevant to establish a doze. That is all.
Besides I dont take anything now which can be considered naive. So you see human factor is not there. And that is upsetting.
That is why we still have no cure for hbv because of how are things are done.
Read the definitions of trials before you go for a visit...
http://clinicaltrials.gov/ct2/results?term=9620
The study title clearly says "IN TREATMENT NAIVE PATIENTS". Which part you do not understand ?
And by definition its a trial, so if you participate then yes YOUR ARE MONKEY. And how do you imagine to test a new drugs other than by giving it to one placebo group and one normal ? They need to show it in comparison with placebo to be approved that it even works.
I have my copy of trial agreement for another GILEAD sponsored trial, what part do you want me to type here? Sorry to hear you had bad experience, in my case I'm very happy I can get good drugs and tests for free.
china/russia is already the biggest world economy, the rest is just printing loads of paper that is later called money to keep dying economies alive
veteran: I hope the Chinese can release their version of imiquimod pill so we can order it from Hong-Kong to save hassle.
donot hope anything from china though it is very simple for them to launch cheap immiquimoid oral pill. they are now biggest hub of hvb people, but china is care less. china is busy in cheap plastic toys, weapons and cheap mobile phones, this way he wants to become super power. china must understand that being world super power is not only about economy but it is about some real contribution to whole world/humanity, very healthy civilians (to reduce burden on economy which is billions of doller on hep b in china) and leadership in all fields specially cutting edge research and developements. decades ago usa was the leader now its open for all like china, russia and european countries. from recent developements,it seems that russia is taking initiative to take lead. usa is sleeping deep, from long time no developement from usa which proves it as world leader. hep b cure is a good opportunity for them to put their world leadership again. but i think i fabour russia in hep b context.
i m hopefull that there will be something good for us from myercludex b trial.
no way, these type of un professional things were not expected, atleast from GILEAD a bright company. shocking, the people like gilead are doing the inefficient, non scientific and shameful things like this.
yes veteran, very correct, it is not medicine now, it has become a booming industry. and if done this way, these things can't be called clinical trial but product testing. and FDA is their DON and God Father.
it must change. and gilead must check their working, because it is quite a reputed company in papients eye, may be thats because we did not know its inside truths. now we know about gilead too.
p.s. I wish everything was so peachy when it comes to health care, I wish it was not like this.
I wish health insurance companies would not deny health care coverage to HBV patients. I wish the doctors cared about what they actually do. So if you want proof I have 7 years of it.
They turned me down simply on the basis that I am not treatment naive patient.
This is the second time I am trying without of luck getting into this trial. At two different facilities that conduct these trials.. How is that for a proof from a real patient!
First time it was that I take ETV instead of TDF.. Now it is not treatment naive.
So if you have a better suggestion how can I get to try this medication let me know..
There are arms of this trial that take people currently taking NUCs - please provide proof if you make these claims
I hope the Chinese can release their version of imiquimod pill so we can order it from Hong-Kong to save hassle.
Really there is so much hassle with these clinical trials, that it is really not worth it to participate if they are conducted like this.