Thanks. It looks interesting, but very few details:
SB 9200 Activates RIG-I, Stimulating Interferon Production and Also Interferes Directly with Viral Replication
• Activates RIG-I and triggers the signaling cascade for antiviral action
• Interferes with viral proteins by preventing them from binding, blocking their
progression or displacing them from viral RNA thereby inhibiting viral replication.
"After successful preclinical studies, this new oral drug, now called SB 44, may soon be moving into clinical trials to test its effectiveness in humans for the treatment of chronic HBV infections." - do you know were this preclinical test were done ?
http://www.springbankpharm.com/hepatitis.html
Just found out about this new drug. Will try to get more info.
That is good news but at the rate they move to approve these things it takes 10 or more years. There just has to be a better way to all this.
update
http://springbankpharm.com/spring-bank-pharmaceuticals-completes-22-million-financing-proceeds-support-phase-ii-clinical-development-sb-9200-hepatitis-b/
I can not find anywhere results of Phase I :/
they have a presentation at March 20-21, 2015
http://www.760kfmb.com/story/28405619/spring-bank-pharmaceuticals-to-present-novel-approach-to-hepatitis-b-treatment-at-the-2015-aasld-and-industry-colloquium
thanks :) good to know that somethings going on
: $ARWR according to the Barclay's presentation, ARC520 data to be reported 'end of Q2',hope some good news.
yep. study finishes in April https://clinicaltrials.gov/ct2/show/NCT02065336
Phase II clinical trials for SB 9200 in HBV-infected patients are expected to begin in late 2015.