HBSAG - Status

[kanchi213]

My HBV DNA quantitative PCR method is 3286 iu/ml or 19326 copeis/ml  and Elastrography of liver ARFI value is ranging from 0.67 - 1.23 mtr/sec.
Doctor has advised me to take baraclade .5mg for next months and i am feeling acute pain in abdomin.

I am confused and not sure what to do..rather blindly take doctor advise on medication.

Please advise me status ..is my viral load is dangrous and should i have take the medicine..

[kanchi213]

all other test are normal..i am confused and worried..doctor tell me symptoms will come down slowly and continue entecavir for 3 months..once your HBV is down to undectable range your will not get pain.

[stef2011]

pain is not due to hbv, liver has no nerves so no pain can come from the liver

[kanchi213]

I am unable to understand after taking baraclude.5 mg for 6 weeks.. the pain is not reduced i am getting severe pain some time upper quardent of abdomein ribcage. some time under abdomein. few times in left side chest...i wounder with such low level of Viral Load 3288 iu/ml ALT slightly higer 48 why i am getting such high pain
I some time fell its not my liver is causing their might be somethings else but my gall bladder, kidneys report are normal.
Please tell me is this pain is because of Heb B or due to anyother reason.
what test do i need get  done which tells its only because of Heb B or its due to others ?

[stef2011]

i think it is ok to take entecavir for at least 3 years and after this period you can consider intf add on or myrcludex if available then

i dont think it is of any use to start intf+entecavir all at once you need hbvdna und and hbsag to decrease for intf to work for sure

[kanchi213]

Thank you stephen. Also, I would like to take stef opinon on the same..whether I can start interferon + ent/tenofovir

I have tested for HBSAG quantitative and the results are 10025 iu/ml. I am worried now since i feel its at a higher side.

Please advise me medication
HBSAG +
HBEAG : Negative
HBEAB : Postive
ALT : 48 ( Range 15 - 40 )
HBV DNA : 3286 iu/ml
HBSAG Quantitative : 10025 iu/ml cutt off . >0.05 iu/ml
Aslo, I am having sever discomfort/ acute burning sensation or pain (confused to discribe my position) in under upper abdomin right side...excatly where my liveris situated.
Fibroscan / ARFI  : F1 or ARFI range .67 to 1.23 m/s

Doctor advised me to take Baraclude on Nov 25 2012 and i have started from the same date.

Please advise what is the best medication for me and  how can i live better

[StephenCastlecrag]

It is difficult to say whether you have developed HBeAg negative chronic Hepatitis B. Normally, one would like to see whether the rise in hbvdna was persistent. However, since you have started Entecavir, your hbdna should level drop and so would your ALT. At the moment, it seems you would have to take Entecavir for at least several years. The rule to determine when to stop taking Entecavir is not well defined yet. Some research seems to indicate it can be guided by the level of HBsAg. The chance of seroconverting your HBsAg is very very small.

As for your pain, hope you are getting better. Some patients complain of a dull pain, but very few complain of an acute pain.